BS3150

antibody from Bioworld Technology, Inc
Targeting: NOC2L DKFZP564C186, NET15, NET7, NIR, PPP1R112
Provider product page for BS3150
Western blot
Immunohistochemistry

Antibody data

Product number
BS3150 - Provider product page
Provider
Bioworld Technology, Inc
Product name
NOC2L (I634) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 602-650 of Human NOC2L.
Description
GADD 153, a growth arrest and DNA damage-inducible gene, encodes a C/EBP-related nuclear protein. This protein has also been designated C/EBP-homologous protein (CHOP-10 or C/EBP zeta). GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase during cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD 153 dimers away from ¡ùclassical¡ì C/EBP binding sites, recognizing instead unique ¡ùnonclassical¡ì sites. Thus, GADD 153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells. GADD 153 belongs to the CBF/MAK21 family, which also includes NOC2L, NOC3L and NOC4L. NOC2L is a 749 amino acid nuclear protein that may play a role in cell cycle regulation.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NOC2L protein structure - BS3150 shown in red.