Tissue expression
Cell line expression
Protein structure
SPTLC2
Serine palmitoyltransferase long chain base subunit 2hLCB2a, KIAA0526, LCB2, LCB2A
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011]
Top validated antibodies |
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Proteintech Group | ![]() |
15 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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Cusabio Biotech Co., Ltd | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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