Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 13997-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13997-1-AP, RRID:AB_10860100
- Product name
- Cryptochrome 2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Cryptochrome 2 antibody (Cat. #13997-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.
Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration.
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
CircRNA-vgll3 promotes osteogenic differentiation of adipose-derived mesenchymal stem cells via modulating miRNA-dependent integrin α5 expression.
Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle.
Inhibition of CRY2 by STAT3/miRNA-7-5p Promotes Osteoblast Differentiation through Upregulation of CLOCK/BMAL1/P300 Expression.
Cryptochromes-Mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism.
Hydrogen peroxide modulates clock gene expression via PRX2-STAT3-REV-ERBα/β pathway.
The NRON complex controls circadian clock function through regulated PER and CRY nuclear translocation.
G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment.
Jiao-tai-wan Up-regulates Hypothalamic and Peripheral Circadian Clock Gene Cryptochrome and Activates PI3K/AKT Signaling in Partially Sleep-deprived Rats.
Effect of Jiaotai Pill () on intestinal damage in partially sleep deprived rats.
KPNB1 mediates PER/CRY nuclear translocation and circadian clock function.
Barajas JM, Lin CH, Sun HL, Alencastro F, Zhu AC, Aljuhani M, Navari L, Yilmaz SA, Yu L, Corps K, He C, Duncan AW, Ghoshal K
The American journal of pathology 2022 Jan;192(1):56-71
The American journal of pathology 2022 Jan;192(1):56-71
Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration.
Tan X, Cao F, Tang F, Lu C, Yu Q, Feng S, Yang Z, Chen S, He X, He J, Weng L, Sun L
Journal of immunology research 2021;2021:9995869
Journal of immunology research 2021;2021:9995869
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Wan X, Zhu L, Zhao L, Peng L, Xiong J, Yang W, Yuan J, Liang F, Zhang K, Chen K
Cell death & disease 2021 Mar 19;12(4):301
Cell death & disease 2021 Mar 19;12(4):301
CircRNA-vgll3 promotes osteogenic differentiation of adipose-derived mesenchymal stem cells via modulating miRNA-dependent integrin α5 expression.
Zhang D, Ni N, Wang Y, Tang Z, Gao H, Ju Y, Sun N, He X, Gu P, Fan X
Cell death and differentiation 2021 Jan;28(1):283-302
Cell death and differentiation 2021 Jan;28(1):283-302
Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle.
Lee Y, Fong SY, Shon J, Zhang SL, Brooks R, Lahens NF, Chen D, Dang CV, Field JM, Sehgal A
Science advances 2021 Feb;7(7)
Science advances 2021 Feb;7(7)
Inhibition of CRY2 by STAT3/miRNA-7-5p Promotes Osteoblast Differentiation through Upregulation of CLOCK/BMAL1/P300 Expression.
Tang Z, Xu T, Li Y, Fei W, Yang G, Hong Y
Molecular therapy. Nucleic acids 2020 Mar 6;19:865-876
Molecular therapy. Nucleic acids 2020 Mar 6;19:865-876
Cryptochromes-Mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism.
Rizzini L, Levine DC, Perelis M, Bass J, Peek CB, Pagano M
Current biology : CB 2019 Jun 17;29(12):1954-1962.e4
Current biology : CB 2019 Jun 17;29(12):1954-1962.e4
Hydrogen peroxide modulates clock gene expression via PRX2-STAT3-REV-ERBα/β pathway.
Ji G, Lv K, Chen H, Wang Y, Zhang Y, Li Y, Qu L
Free radical biology & medicine 2019 Dec;145:312-320
Free radical biology & medicine 2019 Dec;145:312-320
The NRON complex controls circadian clock function through regulated PER and CRY nuclear translocation.
Lee Y, Shen Y, Francey LJ, Ramanathan C, Sehgal A, Liu AC, Hogenesch JB
Scientific reports 2019 Aug 15;9(1):11883
Scientific reports 2019 Aug 15;9(1):11883
G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment.
Lee Y, Lahens NF, Zhang S, Bedont J, Field JM, Sehgal A
PLoS biology 2019 Apr;17(4):e3000228
PLoS biology 2019 Apr;17(4):e3000228
Jiao-tai-wan Up-regulates Hypothalamic and Peripheral Circadian Clock Gene Cryptochrome and Activates PI3K/AKT Signaling in Partially Sleep-deprived Rats.
Huang WY, Zou X, Lu FE, Su H, Zhang C, Ren YL, Fang K, Xu LJ, Wang KF, Chen QJ, Dong H
Current medical science 2018 Aug;38(4):704-713
Current medical science 2018 Aug;38(4):704-713
Effect of Jiaotai Pill () on intestinal damage in partially sleep deprived rats.
Huang WY, Zou X, Lu FE, Zhang C, Ren YL, Xu LJ, Wang KF, Dong H
Chinese journal of integrative medicine 2017 Dec;23(12):901-907
Chinese journal of integrative medicine 2017 Dec;23(12):901-907
KPNB1 mediates PER/CRY nuclear translocation and circadian clock function.
Lee Y, Jang AR, Francey LJ, Sehgal A, Hogenesch JB
eLife 2015 Aug 29;4
eLife 2015 Aug 29;4
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The Cryptochrome 2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Cryptochrome 2. This antibody recognizes human,mouse,rat antigen. The Cryptochrome 2 antibody has been validated for the following applications: ELISA, WB analysis.