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SMAD3
SMAD family member 3HsT17436, JV15-2, MADH3
The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. It also functions as a tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, Nov 2019]
Top validated antibodies |
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| Invitrogen Antibodies |  51-1500 |
82 references | Polyclonal |
WB
EL
ICC
IHC
FC
ChIP
OA
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| GeneTex | GTX111123 |
1 references | Polyclonal |
WB
ICC
IP
IHC
ChIP
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| Proteintech Group | 25494-1-AP |
73 references | Polyclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN954841 |
4 references | Polyclonal |
WB
ICC
IHC
FC
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| Novus Biologicals | H00004088-M02 |
1 references | Monoclonal |
WB
EL
ICC
IHC
PLA
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