BS8137

antibody from Bioworld Technology, Inc
Targeting: PHF21A BHC80, BM-006, KIAA1696
Provider product page for BS8137
Western blot
Immunohistochemistry

Antibody data

Product number
BS8137 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PHF21A polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PHF21A.
Description
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A (PHD finger protein 21A), also known as BRAF35-HDAC complex protein BHC80, is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PHF21A protein structure - BS8137 shown in red.