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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- MAB4235 - Provider product page
- Provider
- R&D Systems
- Product name
- Human/Mouse Integrin alpha 11 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human and mouse Integrin alpha 11 in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant human Integrin alpha 2, alpha 10, alpha X, or alpha L.
- Reactivity
- Human, Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Antigen sequence
EAW77820- Isotype
- IgG
- Antibody clone number
- 396214
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency.
PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis.
Cardiomyocyte contractile status is associated with differences in fibronectin and integrin interactions.
Tharkeshwar AK, Trekker J, Vermeire W, Pauwels J, Sannerud R, Priestman DA, Te Vruchte D, Vints K, Baatsen P, Decuypere JP, Lu H, Martin S, Vangheluwe P, Swinnen JV, Lagae L, Impens F, Platt FM, Gevaert K, Annaert W
Scientific reports 2017 Jan 30;7:41408
Scientific reports 2017 Jan 30;7:41408
PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis.
Martin K, Pritchett J, Llewellyn J, Mullan AF, Athwal VS, Dobie R, Harvey E, Zeef L, Farrow S, Streuli C, Henderson NC, Friedman SL, Hanley NA, Piper Hanley K
Nature communications 2016 Aug 18;7:12502
Nature communications 2016 Aug 18;7:12502
Cardiomyocyte contractile status is associated with differences in fibronectin and integrin interactions.
Wu X, Sun Z, Foskett A, Trzeciakowski JP, Meininger GA, Muthuchamy M
American journal of physiology. Heart and circulatory physiology 2010 Jun;298(6):H2071-81
American journal of physiology. Heart and circulatory physiology 2010 Jun;298(6):H2071-81
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of Human Integrin alpha 11 by Western Blot. Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line and human heart tissue. PVDF membrane was probed with 2 µg/mL of Human/Mouse Integrin alpha 11 Monoclonal Antibody (Catalog # MAB4235) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005). A specific band was detected for Integrin alpha 11 at approximately 150 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
