BS7703

antibody from Bioworld Technology, Inc
Targeting: CLN3 BTN1, BTS, JNCL
Provider product page for BS7703
Western blot
Immunohistochemistry

Antibody data

Product number
BS7703 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CLN3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CLN3.
Description
CLN3 is a highly glycosylated, hydrophobic, 438-amino acid protein with 6 transmembrane domains. The CLN3 protein localizes to the lysosomal membrane and plays a role in lysosomal function. It may act as a chaperone involved in the folding and unfolding of other proteins, namely subunit C of the ATP synthase complex. Mutations in the CLN3 gene cause Batten disease, a recessively inherited neurodegenerative disorder of childhood caused by lysosomal accumulation of hydrophobic material, mainly ATP synthase subunit C. Batten disease is the most common form of a group of disorders known as neuronal ceroid lipofuscinoses (NCLs). Symptoms of Batten disease include progressive loss of vision, seizures, and psychomotor disturbances.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CLN3 protein structure - BS7703 shown in red.