Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 16534-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16534-1-AP, RRID:AB_2087511
- Product name
- CTHRC1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CTHRC1 antibody (Cat. #16534-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hyperdense Pancreatic Ductal Adenocarcinoma: Clinical Characteristics and Proteomic Landscape.
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Identification of Overexpressed Genes in Malignant Pleural Mesothelioma.
CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway.
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
CTHRC1 affects malignant tumor cell behavior and is regulated by miR-30e-5p in human prostate cancer.
CTHRC1 May Serve As A Prognostic Biomarker For Hepatocellular Carcinoma.
Pirfenidone attenuates lung fibrotic fibroblast responses to transforming growth factor-β1.
CTHRC1 promotes M2-like macrophage recruitment and myometrial invasion in endometrial carcinoma by integrin-Akt signaling pathway.
CTHRC1 mediates IL‑1β‑induced apoptosis in chondrocytes via JNK1/2 signaling.
Collagen triple helix repeat containing 1 (CTHRC1) activates Integrin β3/FAK signaling and promotes metastasis in ovarian cancer.
Lentivirus-Mediated Knockdown of CTHRC1 Inhibits Osteosarcoma Cell Proliferation and Migration.
SP1-mediated microRNA-520d-5p suppresses tumor growth and metastasis in colorectal cancer by targeting CTHRC1.
MiR-9 inhibits Schwann cell migration by targeting Cthrc1 following sciatic nerve injury.
Xu H, Hua J, Meng Q, Wang X, Xu J, Wang W, Zhang B, Liu J, Liang C, Yu X, Shi S
Frontiers in oncology 2021;11:640820
Frontiers in oncology 2021;11:640820
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Yuan K, Sun Y, Ji Y
Balkan medical journal 2021 May;38(3):177-182
Balkan medical journal 2021 May;38(3):177-182
Identification of Overexpressed Genes in Malignant Pleural Mesothelioma.
Morani F, Bisceglia L, Rosini G, Mutti L, Melaiu O, Landi S, Gemignani F
International journal of molecular sciences 2021 Mar 8;22(5)
International journal of molecular sciences 2021 Mar 8;22(5)
CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway.
Bai Y, Yin K, Su T, Ji F, Zhang S
OncoTargets and therapy 2020;13:5743-5753
OncoTargets and therapy 2020;13:5743-5753
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
Jiang F, Chen Y, Ren S, Li Z, Sun K, Xing Y, Zhu Y, Piao D
International journal of oncology 2020 Jul;57(1):183-196
International journal of oncology 2020 Jul;57(1):183-196
CTHRC1 affects malignant tumor cell behavior and is regulated by miR-30e-5p in human prostate cancer.
Ma Z, Chao F, Wang S, Song Z, Zhuo Z, Zhang J, Xu G, Chen G
Biochemical and biophysical research communications 2020 Apr 30;525(2):418-424
Biochemical and biophysical research communications 2020 Apr 30;525(2):418-424
CTHRC1 May Serve As A Prognostic Biomarker For Hepatocellular Carcinoma.
Zhou H, Su L, Liu C, Li B, Li H, Xie Y, Sun D
OncoTargets and therapy 2019;12:7823-7831
OncoTargets and therapy 2019;12:7823-7831
Pirfenidone attenuates lung fibrotic fibroblast responses to transforming growth factor-β1.
Jin J, Togo S, Kadoya K, Tulafu M, Namba Y, Iwai M, Watanabe J, Nagahama K, Okabe T, Hidayat M, Kodama Y, Kitamura H, Ogura T, Kitamura N, Ikeo K, Sasaki S, Tominaga S, Takahashi K
Respiratory research 2019 Jun 11;20(1):119
Respiratory research 2019 Jun 11;20(1):119
CTHRC1 promotes M2-like macrophage recruitment and myometrial invasion in endometrial carcinoma by integrin-Akt signaling pathway.
Li LY, Yin KM, Bai YH, Zhang ZG, Di W, Zhang S
Clinical & experimental metastasis 2019 Aug;36(4):351-363
Clinical & experimental metastasis 2019 Aug;36(4):351-363
CTHRC1 mediates IL‑1β‑induced apoptosis in chondrocytes via JNK1/2 signaling.
Zhang Q, Yin ZS, Zhang FW, Cao K, Sun HY
International journal of molecular medicine 2018 Apr;41(4):2270-2278
International journal of molecular medicine 2018 Apr;41(4):2270-2278
Collagen triple helix repeat containing 1 (CTHRC1) activates Integrin β3/FAK signaling and promotes metastasis in ovarian cancer.
Guo B, Yan H, Li L, Yin K, Ji F, Zhang S
Journal of ovarian research 2017 Oct 11;10(1):69
Journal of ovarian research 2017 Oct 11;10(1):69
Lentivirus-Mediated Knockdown of CTHRC1 Inhibits Osteosarcoma Cell Proliferation and Migration.
Sang W, Zhu L, Ma J, Lu H, Wang C
Cancer biotherapy & radiopharmaceuticals 2016 Apr;31(3):91-8
Cancer biotherapy & radiopharmaceuticals 2016 Apr;31(3):91-8
SP1-mediated microRNA-520d-5p suppresses tumor growth and metastasis in colorectal cancer by targeting CTHRC1.
Yan L, Yu J, Tan F, Ye GT, Shen ZY, Liu H, Zhang Y, Wang JF, Zhu XJ, Li GX
American journal of cancer research 2015;5(4):1447-59
American journal of cancer research 2015;5(4):1447-59
MiR-9 inhibits Schwann cell migration by targeting Cthrc1 following sciatic nerve injury.
Zhou S, Gao R, Hu W, Qian T, Wang N, Ding G, Ding F, Yu B, Gu X
Journal of cell science 2014 Mar 1;127(Pt 5):967-76
Journal of cell science 2014 Mar 1;127(Pt 5):967-76
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 16534-1-AP(CTHRC1 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 16534-1-AP(CTHRC1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CTHRC1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CTHRC1. This antibody recognizes human,mouse,rat antigen. The CTHRC1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.