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Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [2]
- ELISA [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- H00006241-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00006241-M01, RRID:AB_547899
- Product name
- Mouse Monoclonal RRM2 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. RRM2 - ribonucleotide reductase M2 polypeptide
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references APLP2, RRM2, and PRC1: New Putative Markers for the Differential Diagnosis of Thyroid Follicular Lesions.
ABCE1 is essential for S phase progression in human cells.
Expression of Ribonucleotide Reductase Subunit-2 and Thymidylate Synthase Correlates with Poor Prognosis in Patients with Resected Stages I-III Non-Small Cell Lung Cancer.
RRM1 maintains centrosomal integrity via CHK1 and CDK1 signaling during replication stress.
Comparison of quantitative performance of three fluorescence labels in CE/LIF analysis of aspartate and glutamate in brain microdialysate.
KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines.
Epstein-Barr virus episome stability is coupled to a delay in replication timing.
Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.
Castelblanco E, Zafon C, Maravall J, Gallel P, Martinez M, Capel I, Bella MR, Halperin I, Temprana J, Iglesias C, Puig-Domingo M, Robledo M, Matias-Guiu X, Mauricio D
Thyroid : official journal of the American Thyroid Association 2017 Jan;27(1):59-66
Thyroid : official journal of the American Thyroid Association 2017 Jan;27(1):59-66
ABCE1 is essential for S phase progression in human cells.
Toompuu M, Kärblane K, Pata P, Truve E, Sarmiento C
Cell cycle (Georgetown, Tex.) 2016 May 2;15(9):1234-47
Cell cycle (Georgetown, Tex.) 2016 May 2;15(9):1234-47
Expression of Ribonucleotide Reductase Subunit-2 and Thymidylate Synthase Correlates with Poor Prognosis in Patients with Resected Stages I-III Non-Small Cell Lung Cancer.
Grossi F, Dal Bello MG, Salvi S, Puzone R, Pfeffer U, Fontana V, Alama A, Rijavec E, Barletta G, Genova C, Sini C, Ratto GB, Taviani M, Truini M, Merlo DF
Disease markers 2015;2015:302649
Disease markers 2015;2015:302649
RRM1 maintains centrosomal integrity via CHK1 and CDK1 signaling during replication stress.
Kim SH, Park ER, Joo HY, Shen YN, Hong SH, Kim CH, Singh R, Lee KH, Shin HJ
Cancer letters 2014 May 1;346(2):249-56
Cancer letters 2014 May 1;346(2):249-56
Comparison of quantitative performance of three fluorescence labels in CE/LIF analysis of aspartate and glutamate in brain microdialysate.
Wagner Z, Tábi T, Zachar G, Csillag A, Szöko E
Electrophoresis 2011 Oct;32(20):2816-22
Electrophoresis 2011 Oct;32(20):2816-22
KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines.
Yoshida Y, Tsunoda T, Doi K, Tanaka Y, Fujimoto T, Machida T, Ota T, Koyanagi M, Takashima Y, Sasazuki T, Kuroki M, Iwasaki A, Shirasawa S
Anticancer research 2011 Jul;31(7):2535-9
Anticancer research 2011 Jul;31(7):2535-9
Epstein-Barr virus episome stability is coupled to a delay in replication timing.
Zhou J, Snyder AR, Lieberman PM
Journal of virology 2009 Mar;83(5):2154-62
Journal of virology 2009 Mar;83(5):2154-62
Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.
Tang LY, Deng N, Wang LS, Dai J, Wang ZL, Jiang XS, Li SJ, Li L, Sheng QH, Wu DQ, Li L, Zeng R
Molecular & cellular proteomics : MCP 2007 Nov;6(11):1952-67
Molecular & cellular proteomics : MCP 2007 Nov;6(11):1952-67
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: RRM2 Antibody (1E1) [H00006241-M01] - RRM2 expression in HeLa NE ( Cat # L013V3 ).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: RRM2 Antibody (1E1) [H00006241-M01] - RRM2 monoclonal antibody (M01), clone 1E1. Analysis of RRM2 expression in HepG2.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: RRM2 Antibody (1E1.) [H00006241-M01] - RRM2 Antibody (1E1) [H00006241-M01] - Detection limit for recombinant GST tagged RRM2 is approximately 0.03ng/ml as a capture antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunocytochemistry/Immunofluorescence: RRM2 Antibody (1E1) [H00006241-M01] - Analysis of monoclonal antibody to RRM2 on HeLa cell. Antibody concentration 10 ug/ml.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: RRM2 Antibody (1E1) [H00006241-M01] - Analysis of monoclonal antibody to RRM2 on formalin-fixed paraffin-embedded human stomach. Antibody concentration 1.5 ug/ml.
