Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS6602 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- FABP2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human FABP2.
- Description
- ?Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). Intestinal FABP (I-FABP) is an abundant cytosolic protein abundant in small intestine epithelial cells. The human gene maps to chromosome 4q26 and has a polymorphism at codon 54, which confers an alanine-encoding allele and a threonine-encoding allele. Threonine at position 54 is associated with increased fat oxidation and Insulin resistance.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot analysis of extracts of 293T cell lines, using FABP2 antibody.