Tissue expression
Cell line expression
Protein structure
LPIN1
Lipin 1KIAA0188
This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. [provided by RefSeq, Mar 2017]
Top validated antibodies |
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Novus Biologicals | NBP2-76845 | Monoclonal |
WB
ICC
IP
IHC
FC
|
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Proteintech Group | 27026-1-AP | 2 references | Polyclonal |
WB
EL
IP
IHC |
|
antibodies-online | ABIN554177 | 3 references | Polyclonal |
WB
ICC
IHC
|
|
Boster Biological Technology | A02467-1 | Polyclonal |
WB
ICC
IP
IHC
FC
|
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LSBio | LS-B10117 | Polyclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
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Recommended by provider