AF1618

antibody from Novus Biologicals

Targeting: AMHR2 MISR2, MISRII

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Blocking/Neutralizing (Data presented on provider website)

Antibody Data

Product number

AF1618

Provider

Novus Biologicals

Product name

Goat Polyclonal MIS RII/AMHR2 Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects rat MIS RII in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) TGF-beta RII, rhTGF-beta RIII, recombinant mouse (rm) TGF-beta RI, and rmTGF-beta RII is observed.

Reactivity

Rat

Host

Goat

Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism.

Malone SA, Papadakis GE, Messina A, Mimouni NEH, Trova S, Imbernon M, Allet C, Cimino I, Acierno J, Cassatella D, Xu C, Quinton R, Szinnai G, Pigny P, Alonso-Cotchico L, Masgrau L, Maréchal JD, Prevot V, Pitteloud N, Giacobini P
eLife 2019 Jul 10;8

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Anti-Müllerian hormone: a new actor of sexual dimorphism in pituitary gonadotrope activity before puberty.

Garrel G, Racine C, L'Hôte D, Denoyelle C, Guigon CJ, di Clemente N, Cohen-Tannoudji J
Scientific reports 2016 Mar 31;6:23790

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Müllerian inhibiting substance contributes to sex-linked biases in the brain and behavior.

Wang PY, Protheroe A, Clarkson AN, Imhoff F, Koishi K, McLennan IS
Proceedings of the National Academy of Sciences of the United States of America 2009 Apr 28;106(17):7203-8