ZC4H2

This gene encodes a member of the zinc finger domain-containing protein family. This family member has a C-terminal zinc finger domain that is characterized by four cysteine residues and two histidine residues, and it also includes a coiled-coil region. This protein has been detected as an autoantigen in hepatocellular carcinoma patients. This gene has been identified as a potential candidate for X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Description

Zinc finger C4H2-type containing

Tissue specificity

Low tissue specificity

Subcell location

Vesicles, Microtubules

Predicted location

Intracellular

Protein family

Disease related genes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

X (64915802 - 65034713)

Ensembl ID

ENSG00000126970  (ver. 103.38)

Orthologs

Mouse Zc4h2: ENSMUSG00000035062

UniProt

Q9NQZ6

neXtProt

NX_Q9NQZ6

Human splice variants
Mouse splice variants

Protein structure