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- Goat Polyclonal AIF-1/Iba1 Antibody
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Submitted references Gender Differences in Neurodegeneration, Neuroinflammation and Na+-Ca2+ Exchangers in the Female A53T Transgenic Mouse Model of Parkinson's Disease.
The inhibition of Kir2.1 potassium channels depolarizes spinal microglial cells, reduces their proliferation, and attenuates neuropathic pain.
N,N-dimethyltryptamine reduces infarct size and improves functional recovery following transient focal brain ischemia in rats.
Distinct dual roles of p-Tyr42 RhoA GTPase in tau phosphorylation and ATP citrate lyase activation upon different Aβ concentrations.
Cocaine self-administration differentially activates microglia in the mouse brain.
Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2.
Robust neuroinflammation and perivascular pathology in rTg-DI rats, a novel model of microvascular cerebral amyloid angiopathy.
Vascular endothelial growth factor receptor 1 in glioblastoma‑associated microglia/macrophages.
Ultrastructural characterization of mitochondrial damage in experimental autoimmune neuritis.
Microglial activation contributes to depressive-like behavior in dopamine D3 receptor knockout mice.
Nanoscopic Insights of Amphiphilic Peptide against the Oligomer Assembly Process to Treat Huntington's Disease.
Anxiolytic effects of polydatin through the blockade of neuroinflammation in a chronic pain mouse model.
Inhibition of Piezo1 attenuates demyelination in the central nervous system.
Differential Gamma-Synuclein Expression in Acute and Chronic Retinal Ganglion Cell Death in the Retina and Optic Nerve.
Nogo-A-targeting antibody promotes visual recovery and inhibits neuroinflammation after retinal injury.
Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System.
Neutrophil-selective deletion of Cxcr2 protects against CNS neurodegeneration in a mouse model of multiple sclerosis.
MANF delivery improves retinal homeostasis and cell replacement therapies in ageing mice.
Isolation Methods for Human CD34 Subsets Using Fluorescent and Magnetic Activated Cell Sorting: an In Vivo Comparative Study.
Inhibiting endogenous tissue plasminogen activator enhanced neuronal apoptosis and axonal injury after traumatic brain injury.
S100 Calcium-Binding Protein A9 Knockout Contributes to Neuroprotection and Functional Improvement after Traumatic Brain Injury.
Chemogenetic Modulation of Orexin Neurons Reverses Changes in Anxiety and Locomotor Activity in the A53T Mouse Model of Parkinson's Disease.
Activation of TRPV1 Contributes to Recurrent Febrile Seizures via Inhibiting the Microglial M2 Phenotype in the Immature Brain.
Non-cell autonomous modulation of tyrosine hydroxylase by HMGB1 released from astrocytes in an acute MPTP-induced Parkinsonian mouse model.
NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress.
TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease.
Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome.
Norvaline Restores the BBB Integrity in a Mouse Model of Alzheimer's Disease.
Pharmacological and chemogenetic orexin/hypocretin intervention ameliorates Hipp-dependent memory impairment in the A53T mice model of Parkinson's disease.
Aryl hydrocarbon receptor modulates stroke-induced astrogliosis and neurogenesis in the adult mouse brain.
TRPV1 mediates astrocyte activation and interleukin-1β release induced by hypoxic ischemia (HI).
Adiponectin suppresses amyloid-β oligomer (AβO)-induced inflammatory response of microglia via AdipoR1-AMPK-NF-κB signaling pathway.
Resveratrol Regulates BDNF, trkB, PSA-NCAM, and Arc Expression in the Rat Cerebral Cortex after Bilateral Common Carotid Artery Occlusion and Reperfusion.
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Mesenchymal stem cell-derived extracellular vesicles and retinal ischemia-reperfusion.
Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model.
Neutrophil and macrophage influx into the central nervous system are inflammatory components of lethal Rift Valley fever encephalitis in rats.
Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes.
(Pro)renin receptor knockdown in the paraventricular nucleus of the hypothalamus attenuates hypertension development and AT1 receptor-mediated calcium events.
Single-cell analysis reveals T cell infiltration in old neurogenic niches.
Targeting Microglia Using Cx3cr1-Cre Lines: Revisiting the Specificity.
Tracking the evolution of CNS remyelinating lesion in mice with neutral red dye.
Unique microglia expression profile in developing white matter.
Exercise and probiotics attenuate the development of Alzheimer's disease in transgenic mice: Role of microbiome.
Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury.
Removal of microglial-specific MyD88 signaling alters dentate gyrus doublecortin and enhances opioid addiction-like behaviors.
Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution.
Endoplasmic reticulum stress is transmissible in vitro between cells of the central nervous system.
Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation.
Pioglitazone improves working memory performance when administered in chronic TBI.
Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway.
ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury.
Genetic and pharmacological manipulation of glial glutamate transporters does not alter infection-induced seizure activity.
A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth.
Minocycline mitigates the effect of neonatal hypoxic insult on human brain organoids.
Microglia TREM2 is required for electroacupuncture to attenuate neuroinflammation in focal cerebral ischemia/reperfusion rats.
Mast Cells in the Developing Brain Determine Adult Sexual Behavior.
Tetramethylpyrazine ameliorates experimental autoimmune encephalomyelitis by modulating the inflammatory response.
Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline.
L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease.
Phloroglucinol ameliorates cognitive impairments by reducing the amyloid β peptide burden and pro-inflammatory cytokines in the hippocampus of 5XFAD mice.
Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth.
Endothelial Cell-Specific Inactivation of TSPAN12 (Tetraspanin 12) Reveals Pathological Consequences of Barrier Defects in an Otherwise Intact Vasculature.
Lentivirus-mediated overexpression of OTULIN ameliorates microglia activation and neuroinflammation by depressing the activation of the NF-κB signaling pathway in cerebral ischemia/reperfusion rats.
APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.
Prostaglandin Signaling Governs Spike Timing-Dependent Plasticity at Sensory Synapses onto Mouse Spinal Projection Neurons.
Blockade of soluble epoxide hydrolase attenuates post-ischemic neuronal hyperexcitation and confers resilience against stroke with TrkB activation.
Stress-Induced Neuronal Colony Stimulating Factor 1 Provokes Microglia-Mediated Neuronal Remodeling and Depressive-like Behavior.
Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture.
NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency.
Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge.
RGMa mediates reactive astrogliosis and glial scar formation through TGFβ1/Smad2/3 signaling after stroke.
Localization of cannabinoid receptors CB1, CB2, GPR55, and PPARα in the canine gastrointestinal tract.
Increased (pro)renin receptor expression in the subfornical organ of hypertensive humans.
Electroacupuncture Suppresses the NF-κB Signaling Pathway by Upregulating Cylindromatosis to Alleviate Inflammatory Injury in Cerebral Ischemia/Reperfusion Rats.
Dysfunction of Microglial STAT3 Alleviates Depressive Behavior via Neuron-Microglia Interactions.
Injectable nanomedicine hydrogel for local chemotherapy of glioblastoma after surgical resection.
Antarctic Krill Oil Diet Protects against Lipopolysaccharide-Induced Oxidative Stress, Neuroinflammation and Cognitive Impairment.
Inhibitory effect of punicalagin on lipopolysaccharide-induced neuroinflammation, oxidative stress and memory impairment via inhibition of nuclear factor-kappaB.
Cell-type specific differences in promoter activity of the ALS-linked C9orf72 mouse ortholog.
Inhibitory effect of ethanol extract of Nannochloropsis oceanica on lipopolysaccharide-induced neuroinflammation, oxidative stress, amyloidogenesis and memory impairment.
All- Trans-Retinoic Acid Augments the Histopathological Outcome of Neuroinflammation and Neurodegeneration in Lupus-Prone MRL/lpr Mice.
Huperzine A alleviates neuroinflammation, oxidative stress and improves cognitive function after repetitive traumatic brain injury.
Electroacupuncture attenuates learning and memory impairment via activation of α7nAChR-mediated anti-inflammatory activity in focal cerebral ischemia/reperfusion injured rats.
HDAC3 inhibition ameliorates spinal cord injury by immunomodulation.
Progesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling.
Imbalances in Mobilization and Activation of Pro-Inflammatory and Vascular Reparative Bone Marrow-Derived Cells in Diabetic Retinopathy.
Upregulation of neuronal zinc finger protein A20 expression is required for electroacupuncture to attenuate the cerebral inflammatory injury mediated by the nuclear factor-kB signaling pathway in cerebral ischemia/reperfusion rats.
Xenin-induced feeding suppression is not mediated through the activation of central extracellular signal-regulated kinase signaling in mice.
Acceleration of amyloidogenesis and memory impairment by estrogen deficiency through NF-κB dependent beta-secretase activation in presenilin 2 mutant mice.
Reduction of cytosolic phospholipase A2α upregulation delays the onset of symptoms in SOD1G93A mouse model of amyotrophic lateral sclerosis.
Hippocampus-based contextual memory alters the morphological characteristics of astrocytes in the dentate gyrus.
Progesterone receptor signalling in retinal photoreceptor neuroprotection.
Seizure-Induced Sympathoexcitation Is Caused by Activation of Glutamatergic Receptors in RVLM That Also Causes Proarrhythmogenic Changes Mediated by PACAP and Microglia in Rats.
Dynamic changes in the relationship of microglia to cardiovascular neurons in response to increases and decreases in blood pressure.
Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke.
Neuronal Injury, Gliosis, and Glial Proliferation in Two Models of Temporal Lobe Epilepsy.
Role of Acid Sphingomyelinase in Shifting the Balance Between Proinflammatory and Reparative Bone Marrow Cells in Diabetic Retinopathy.
The PGRMC1 Protein Level Correlates with the Binding Activity of a Sigma-2 Fluorescent Probe (SW120) in Rat Brain Cells.
Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium.
Partial depletion of the proinflammatory monocyte population is neuroprotective in the myenteric plexus but not in the basal ganglia in a MPTP mouse model of Parkinson's disease.
The role of cytosolic phospholipase A2 α in amyloid precursor protein induction by amyloid beta1-42 : implication for neurodegeneration.
Expression of Cytoplasmic Gelsolin in Rat Brain After Experimental Subarachnoid Hemorrhage.
The expression of interleukin-6 and its receptor in various brain regions and their roles in exploratory behavior and stress responses.
Vagus nerve stimulation attenuates cerebral ischemia and reperfusion injury via endogenous cholinergic pathway in rat.
Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease.
Domoic acid-induced seizures in California sea lions (Zalophus californianus) are associated with neuroinflammatory brain injury.
Regionally specific expression of high-voltage-activated calcium channels in thalamic nuclei of epileptic and non-epileptic rats.
A small molecule binding HMGB1 and HMGB2 inhibits microglia-mediated neuroinflammation.
Aging-induced Nrf2-ARE pathway disruption in the subventricular zone drives neurogenic impairment in parkinsonian mice via PI3K-Wnt/β-catenin dysregulation.
Plasticity of subventricular zone neuroprogenitors in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease involves cross talk between inflammatory and Wnt/β-catenin signaling pathways: functional consequences for neuroprotection and repair.
A-type K+ currents in intralaminar thalamocortical relay neurons.
The performance of laminin-containing cryogel scaffolds in neural tissue regeneration.
Regulation of toll-like receptor 1 and -2 in neonatal mice brains after hypoxia-ischemia.
Transmission and spreading of tauopathy in transgenic mouse brain.
Irradiation-induced loss of microglia in the young brain.
Intranigral lentiviral delivery of dominant-negative TNF attenuates neurodegeneration and behavioral deficits in hemiparkinsonian rats.
Maternal hypothyroxinemia impairs spatial learning and synaptic nature and function in the offspring.
Glial reactions and degeneration of myelinated processes in spinal cord gray matter in chronic experimental autoimmune encephalomyelitis.
Modulation of inflammatory responses after global ischemia by transplanted umbilical cord matrix stem cells.
P2Y12 receptor upregulation in activated microglia is a gateway of p38 signaling and neuropathic pain.
Contribution of TRPV1 to microglia-derived IL-6 and NFkappaB translocation with elevated hydrostatic pressure.
Age-dependent accumulation of lipofuscin in perivascular and subretinal microglia in experimental mice.
Intracarotid injection of fluorescence activated cell-sorted CD49d-positive neural stem cells improves targeted cell delivery and behavior after stroke in a mouse stroke model.
The synthetic peroxisome proliferator-activated receptor-gamma agonist ciglitazone attenuates neuroinflammation and accelerates encapsulation in bacterial brain abscesses.
The synthetic peroxisome proliferator-activated receptor-gamma agonist ciglitazone attenuates neuroinflammation and accelerates encapsulation in bacterial brain abscesses.
Glial activation links early-life seizures and long-term neurologic dysfunction: evidence using a small molecule inhibitor of proinflammatory cytokine upregulation.
C3d binding to the myelin oligodendrocyte glycoprotein results in an exacerbated experimental autoimmune encephalomyelitis.
C3d binding to the myelin oligodendrocyte glycoprotein results in an exacerbated experimental autoimmune encephalomyelitis.
Expression of allograft inflammatory factor 1 in tissues from patients with systemic sclerosis and in vitro differential expression of its isoforms in response to transforming growth factor beta.
IRT-1, a novel interferon-gamma-responsive transcript encoding a growth-suppressing basic leucine zipper protein.
IRT-1, a novel interferon-gamma-responsive transcript encoding a growth-suppressing basic leucine zipper protein.
Costa G, Sisalli MJ, Simola N, Della Notte S, Casu MA, Serra M, Pinna A, Feliciello A, Annunziato L, Scorziello A, Morelli M
Frontiers in aging neuroscience 2020;12:118
Frontiers in aging neuroscience 2020;12:118
The inhibition of Kir2.1 potassium channels depolarizes spinal microglial cells, reduces their proliferation, and attenuates neuropathic pain.
Gattlen C, Deftu AF, Tonello R, Ling Y, Berta T, Ristoiu V, Suter MR
Glia 2020 Oct;68(10):2119-2135
Glia 2020 Oct;68(10):2119-2135
N,N-dimethyltryptamine reduces infarct size and improves functional recovery following transient focal brain ischemia in rats.
Nardai S, László M, Szabó A, Alpár A, Hanics J, Zahola P, Merkely B, Frecska E, Nagy Z
Experimental neurology 2020 May;327:113245
Experimental neurology 2020 May;327:113245
Distinct dual roles of p-Tyr42 RhoA GTPase in tau phosphorylation and ATP citrate lyase activation upon different Aβ concentrations.
Cap KC, Jung YJ, Choi BY, Hyeon SJ, Kim JG, Min JK, Islam R, Hossain AJ, Chung WS, Suh SW, Ryu H, Park JB
Redox biology 2020 May;32:101446
Redox biology 2020 May;32:101446
Cocaine self-administration differentially activates microglia in the mouse brain.
Burkovetskaya ME, Small R, Guo L, Buch S, Guo ML
Neuroscience letters 2020 May 29;728:134951
Neuroscience letters 2020 May 29;728:134951
Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2.
Zhou X, Wahane S, Friedl MS, Kluge M, Friedel CC, Avrampou K, Zachariou V, Guo L, Zhang B, He X, Friedel RH, Zou H
Nature neuroscience 2020 Mar;23(3):337-350
Nature neuroscience 2020 Mar;23(3):337-350
Robust neuroinflammation and perivascular pathology in rTg-DI rats, a novel model of microvascular cerebral amyloid angiopathy.
Zhu X, Hatfield J, Sullivan JK, Xu F, Van Nostrand WE
Journal of neuroinflammation 2020 Mar 4;17(1):78
Journal of neuroinflammation 2020 Mar 4;17(1):78
Vascular endothelial growth factor receptor 1 in glioblastoma‑associated microglia/macrophages.
Lisi L, Pia Ciotti GM, Chiavari M, Ruffini F, Lacal PM, Graziani G, Navarra P
Oncology reports 2020 Jun;43(6):2083-2092
Oncology reports 2020 Jun;43(6):2083-2092
Ultrastructural characterization of mitochondrial damage in experimental autoimmune neuritis.
Muke I, Sprenger A, Bobylev I, Wiemer V, Barham M, Neiss WF, Lehmann HC
Journal of neuroimmunology 2020 Jun 15;343:577218
Journal of neuroimmunology 2020 Jun 15;343:577218
Microglial activation contributes to depressive-like behavior in dopamine D3 receptor knockout mice.
Wang J, Lai S, Li G, Zhou T, Wang B, Cao F, Chen T, Zhang X, Chen Y
Brain, behavior, and immunity 2020 Jan;83:226-238
Brain, behavior, and immunity 2020 Jan;83:226-238
Nanoscopic Insights of Amphiphilic Peptide against the Oligomer Assembly Process to Treat Huntington's Disease.
He RY, Lai XM, Sun CS, Kung TS, Hong JY, Jheng YS, Liao WN, Chen JK, Liao YF, Tu PH, Huang JJ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Jan;7(2):1901165
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Jan;7(2):1901165
Anxiolytic effects of polydatin through the blockade of neuroinflammation in a chronic pain mouse model.
Guan SY, Zhang K, Wang XS, Yang L, Feng B, Tian DD, Gao MR, Liu SB, Liu A, Zhao MG
Molecular pain 2020 Jan-Dec;16:1744806919900717
Molecular pain 2020 Jan-Dec;16:1744806919900717
Inhibition of Piezo1 attenuates demyelination in the central nervous system.
Velasco-Estevez M, Gadalla KKE, Liñan-Barba N, Cobb S, Dev KK, Sheridan GK
Glia 2020 Feb;68(2):356-375
Glia 2020 Feb;68(2):356-375
Differential Gamma-Synuclein Expression in Acute and Chronic Retinal Ganglion Cell Death in the Retina and Optic Nerve.
Liu Y, Tapia ML, Yeh J, He RC, Pomerleu D, Lee RK
Molecular neurobiology 2020 Feb;57(2):698-709
Molecular neurobiology 2020 Feb;57(2):698-709
Nogo-A-targeting antibody promotes visual recovery and inhibits neuroinflammation after retinal injury.
Baya Mdzomba J, Joly S, Rodriguez L, Dirani A, Lassiaz P, Behar-Cohen F, Pernet V
Cell death & disease 2020 Feb 6;11(2):101
Cell death & disease 2020 Feb 6;11(2):101
Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System.
Koundal S, Elkin R, Nadeem S, Xue Y, Constantinou S, Sanggaard S, Liu X, Monte B, Xu F, Van Nostrand W, Nedergaard M, Lee H, Wardlaw J, Benveniste H, Tannenbaum A
Scientific reports 2020 Feb 6;10(1):1990
Scientific reports 2020 Feb 6;10(1):1990
Neutrophil-selective deletion of Cxcr2 protects against CNS neurodegeneration in a mouse model of multiple sclerosis.
Khaw YM, Cunningham C, Tierney A, Sivaguru M, Inoue M
Journal of neuroinflammation 2020 Feb 4;17(1):49
Journal of neuroinflammation 2020 Feb 4;17(1):49
MANF delivery improves retinal homeostasis and cell replacement therapies in ageing mice.
Neves J, Chirco KR, Cedron-Craft W, Chew S, Zhu J, Jasper H, Lamba DA
Experimental gerontology 2020 Feb 28;134:110893
Experimental gerontology 2020 Feb 28;134:110893
Isolation Methods for Human CD34 Subsets Using Fluorescent and Magnetic Activated Cell Sorting: an In Vivo Comparative Study.
Tripathi H, Peng H, Donahue R, Chelvarajan L, Gottipati A, Levitan B, Al-Darraji A, Gao E, Abdel-Latif A, Berron BJ
Stem cell reviews and reports 2020 Apr;16(2):413-423
Stem cell reviews and reports 2020 Apr;16(2):413-423
Inhibiting endogenous tissue plasminogen activator enhanced neuronal apoptosis and axonal injury after traumatic brain injury.
Zhao JJ, Liu ZW, Wang B, Huang TQ, Guo D, Zhao YL, Song JN
Neural regeneration research 2020 Apr;15(4):667-675
Neural regeneration research 2020 Apr;15(4):667-675
S100 Calcium-Binding Protein A9 Knockout Contributes to Neuroprotection and Functional Improvement after Traumatic Brain Injury.
Qiu X, Ping S, Kyle M, Longo J, Chin L, Zhao LR
Journal of neurotrauma 2020 Apr 1;37(7):950-965
Journal of neurotrauma 2020 Apr 1;37(7):950-965
Chemogenetic Modulation of Orexin Neurons Reverses Changes in Anxiety and Locomotor Activity in the A53T Mouse Model of Parkinson's Disease.
Stanojlovic M, Pallais JP, Kotz CM
Frontiers in neuroscience 2019;13:702
Frontiers in neuroscience 2019;13:702
Activation of TRPV1 Contributes to Recurrent Febrile Seizures via Inhibiting the Microglial M2 Phenotype in the Immature Brain.
Kong W, Wang X, Yang X, Huang W, Han S, Yin J, Liu W, He X, Peng B
Frontiers in cellular neuroscience 2019;13:442
Frontiers in cellular neuroscience 2019;13:442
Non-cell autonomous modulation of tyrosine hydroxylase by HMGB1 released from astrocytes in an acute MPTP-induced Parkinsonian mouse model.
Kim SJ, Ryu MJ, Han J, Jang Y, Lee MJ, Ju X, Ryu I, Lee YL, Oh E, Chung W, Heo JY, Kweon GR
Laboratory investigation; a journal of technical methods and pathology 2019 Sep;99(9):1389-1399
Laboratory investigation; a journal of technical methods and pathology 2019 Sep;99(9):1389-1399
NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress.
Yang B, Figueroa DM, Hou Y, Babbar M, Baringer SL, Croteau DL, Bohr VA
Free radical biology & medicine 2019 Sep;141:47-58
Free radical biology & medicine 2019 Sep;141:47-58
TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease.
Griciuc A, Patel S, Federico AN, Choi SH, Innes BJ, Oram MK, Cereghetti G, McGinty D, Anselmo A, Sadreyev RI, Hickman SE, El Khoury J, Colonna M, Tanzi RE
Neuron 2019 Sep 4;103(5):820-835.e7
Neuron 2019 Sep 4;103(5):820-835.e7
Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome.
Tejera D, Mercan D, Sanchez-Caro JM, Hanan M, Greenberg D, Soreq H, Latz E, Golenbock D, Heneka MT
The EMBO journal 2019 Sep 2;38(17):e101064
The EMBO journal 2019 Sep 2;38(17):e101064
Norvaline Restores the BBB Integrity in a Mouse Model of Alzheimer's Disease.
Polis B, Gurevich V, Assa M, Samson AO
International journal of molecular sciences 2019 Sep 18;20(18)
International journal of molecular sciences 2019 Sep 18;20(18)
Pharmacological and chemogenetic orexin/hypocretin intervention ameliorates Hipp-dependent memory impairment in the A53T mice model of Parkinson's disease.
Stanojlovic M, Pallais JP, Lee MK, Kotz CM
Molecular brain 2019 Oct 30;12(1):87
Molecular brain 2019 Oct 30;12(1):87
Aryl hydrocarbon receptor modulates stroke-induced astrogliosis and neurogenesis in the adult mouse brain.
Chen WC, Chang LH, Huang SS, Huang YJ, Chih CL, Kuo HC, Lee YH, Lee IH
Journal of neuroinflammation 2019 Oct 12;16(1):187
Journal of neuroinflammation 2019 Oct 12;16(1):187
TRPV1 mediates astrocyte activation and interleukin-1β release induced by hypoxic ischemia (HI).
Yang XL, Wang X, Shao L, Jiang GT, Min JW, Mei XY, He XH, Liu WH, Huang WX, Peng BW
Journal of neuroinflammation 2019 May 29;16(1):114
Journal of neuroinflammation 2019 May 29;16(1):114
Adiponectin suppresses amyloid-β oligomer (AβO)-induced inflammatory response of microglia via AdipoR1-AMPK-NF-κB signaling pathway.
Jian M, Kwan JS, Bunting M, Ng RC, Chan KH
Journal of neuroinflammation 2019 May 25;16(1):110
Journal of neuroinflammation 2019 May 25;16(1):110
Resveratrol Regulates BDNF, trkB, PSA-NCAM, and Arc Expression in the Rat Cerebral Cortex after Bilateral Common Carotid Artery Occlusion and Reperfusion.
Serra MP, Boi M, Poddighe L, Melis T, Lai Y, Carta G, Quartu M
Nutrients 2019 May 1;11(5)
Nutrients 2019 May 1;11(5)
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Fang EF, Hou Y, Palikaras K, Adriaanse BA, Kerr JS, Yang B, Lautrup S, Hasan-Olive MM, Caponio D, Dan X, Rocktäschel P, Croteau DL, Akbari M, Greig NH, Fladby T, Nilsen H, Cader MZ, Mattson MP, Tavernarakis N, Bohr VA
Nature neuroscience 2019 Mar;22(3):401-412
Nature neuroscience 2019 Mar;22(3):401-412
Mesenchymal stem cell-derived extracellular vesicles and retinal ischemia-reperfusion.
Mathew B, Ravindran S, Liu X, Torres L, Chennakesavalu M, Huang CC, Feng L, Zelka R, Lopez J, Sharma M, Roth S
Biomaterials 2019 Mar;197:146-160
Biomaterials 2019 Mar;197:146-160
Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model.
Merlini M, Rafalski VA, Rios Coronado PE, Gill TM, Ellisman M, Muthukumar G, Subramanian KS, Ryu JK, Syme CA, Davalos D, Seeley WW, Mucke L, Nelson RB, Akassoglou K
Neuron 2019 Mar 20;101(6):1099-1108.e6
Neuron 2019 Mar 20;101(6):1099-1108.e6
Neutrophil and macrophage influx into the central nervous system are inflammatory components of lethal Rift Valley fever encephalitis in rats.
Albe JR, Boyles DA, Walters AW, Kujawa MR, McMillen CM, Reed DS, Hartman AL
PLoS pathogens 2019 Jun;15(6):e1007833
PLoS pathogens 2019 Jun;15(6):e1007833
Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes.
Diéguez-Hurtado R, Kato K, Giaimo BD, Nieminen-Kelhä M, Arf H, Ferrante F, Bartkuhn M, Zimmermann T, Bixel MG, Eilken HM, Adams S, Borggrefe T, Vajkoczy P, Adams RH
Nature communications 2019 Jun 27;10(1):2817
Nature communications 2019 Jun 27;10(1):2817
(Pro)renin receptor knockdown in the paraventricular nucleus of the hypothalamus attenuates hypertension development and AT1 receptor-mediated calcium events.
Souza LAC, Worker CJ, Li W, Trebak F, Watkins T, Gayban AJB, Yamasaki E, Cooper SG, Drumm BT, Feng Y
American journal of physiology. Heart and circulatory physiology 2019 Jun 1;316(6):H1389-H1405
American journal of physiology. Heart and circulatory physiology 2019 Jun 1;316(6):H1389-H1405
Single-cell analysis reveals T cell infiltration in old neurogenic niches.
Dulken BW, Buckley MT, Navarro Negredo P, Saligrama N, Cayrol R, Leeman DS, George BM, Boutet SC, Hebestreit K, Pluvinage JV, Wyss-Coray T, Weissman IL, Vogel H, Davis MM, Brunet A
Nature 2019 Jul;571(7764):205-210
Nature 2019 Jul;571(7764):205-210
Targeting Microglia Using Cx3cr1-Cre Lines: Revisiting the Specificity.
Zhao XF, Alam MM, Liao Y, Huang T, Mathur R, Zhu X, Huang Y
eNeuro 2019 Jul Aug;6(4)
eNeuro 2019 Jul Aug;6(4)
Tracking the evolution of CNS remyelinating lesion in mice with neutral red dye.
Baydyuk M, Cha DS, Hu J, Yamazaki R, Miller EM, Smith VN, Kelly KA, Huang JK
Proceedings of the National Academy of Sciences of the United States of America 2019 Jul 9;116(28):14290-14299
Proceedings of the National Academy of Sciences of the United States of America 2019 Jul 9;116(28):14290-14299
Unique microglia expression profile in developing white matter.
Staszewski O, Hagemeyer N
BMC research notes 2019 Jul 1;12(1):367
BMC research notes 2019 Jul 1;12(1):367
Exercise and probiotics attenuate the development of Alzheimer's disease in transgenic mice: Role of microbiome.
Abraham D, Feher J, Scuderi GL, Szabo D, Dobolyi A, Cservenak M, Juhasz J, Ligeti B, Pongor S, Gomez-Cabrera MC, Vina J, Higuchi M, Suzuki K, Boldogh I, Radak Z
Experimental gerontology 2019 Jan;115:122-131
Experimental gerontology 2019 Jan;115:122-131
Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury.
Bellver-Landete V, Bretheau F, Mailhot B, Vallières N, Lessard M, Janelle ME, Vernoux N, Tremblay MÈ, Fuehrmann T, Shoichet MS, Lacroix S
Nature communications 2019 Jan 31;10(1):518
Nature communications 2019 Jan 31;10(1):518
Removal of microglial-specific MyD88 signaling alters dentate gyrus doublecortin and enhances opioid addiction-like behaviors.
Rivera PD, Hanamsagar R, Kan MJ, Tran PK, Stewart D, Jo YC, Gunn M, Bilbo SD
Brain, behavior, and immunity 2019 Feb;76:104-115
Brain, behavior, and immunity 2019 Feb;76:104-115
Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution.
Masuda T, Sankowski R, Staszewski O, Böttcher C, Amann L, Sagar, Scheiwe C, Nessler S, Kunz P, van Loo G, Coenen VA, Reinacher PC, Michel A, Sure U, Gold R, Grün D, Priller J, Stadelmann C, Prinz M
Nature 2019 Feb;566(7744):388-392
Nature 2019 Feb;566(7744):388-392
Endoplasmic reticulum stress is transmissible in vitro between cells of the central nervous system.
Sprenkle NT, Lahiri A, Simpkins JW, Meares GP
Journal of neurochemistry 2019 Feb;148(4):516-530
Journal of neurochemistry 2019 Feb;148(4):516-530
Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation.
Kano SI, Choi EY, Dohi E, Agarwal S, Chang DJ, Wilson AM, Lo BD, Rose IVL, Gonzalez S, Imai T, Sawa A
Science signaling 2019 Feb 19;12(569)
Science signaling 2019 Feb 19;12(569)
Pioglitazone improves working memory performance when administered in chronic TBI.
McGuire JL, Correll EA, Lowery AC, Rhame K, Anwar FN, McCullumsmith RE, Ngwenya LB
Neurobiology of disease 2019 Dec;132:104611
Neurobiology of disease 2019 Dec;132:104611
Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway.
Zhao R, Ying M, Gu S, Yin W, Li Y, Yuan H, Fang S, Li M
Neuroscience 2019 Dec 1;422:99-118
Neuroscience 2019 Dec 1;422:99-118
ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury.
Sommer D, Corstjens I, Sanchez S, Dooley D, Lemmens S, Van Broeckhoven J, Bogie J, Vanmierlo T, Vidal PM, Rose-John S, Gou-Fabregas M, Hendrix S
Brain, behavior, and immunity 2019 Aug;80:129-145
Brain, behavior, and immunity 2019 Aug;80:129-145
Genetic and pharmacological manipulation of glial glutamate transporters does not alter infection-induced seizure activity.
Loewen JL, Albertini G, Dahle EJ, Sato H, Smolders IJ, Massie A, Wilcox KS
Experimental neurology 2019 Aug;318:50-60
Experimental neurology 2019 Aug;318:50-60
A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth.
Wang ECE, Dai Z, Ferrante AW, Drake CG, Christiano AM
Cell stem cell 2019 Apr 4;24(4):654-669.e6
Cell stem cell 2019 Apr 4;24(4):654-669.e6
Minocycline mitigates the effect of neonatal hypoxic insult on human brain organoids.
Boisvert EM, Means RE, Michaud M, Madri JA, Katz SG
Cell death & disease 2019 Apr 11;10(4):325
Cell death & disease 2019 Apr 11;10(4):325
Microglia TREM2 is required for electroacupuncture to attenuate neuroinflammation in focal cerebral ischemia/reperfusion rats.
Xu H, Mu S, Qin W
Biochemical and biophysical research communications 2018 Sep 18;503(4):3225-3234
Biochemical and biophysical research communications 2018 Sep 18;503(4):3225-3234
Mast Cells in the Developing Brain Determine Adult Sexual Behavior.
Lenz KM, Pickett LA, Wright CL, Davis KT, Joshi A, McCarthy MM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Sep 12;38(37):8044-8059
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Sep 12;38(37):8044-8059
Tetramethylpyrazine ameliorates experimental autoimmune encephalomyelitis by modulating the inflammatory response.
Bai XY, Wang XF, Zhang LS, Du PC, Cao Z, Hou Y
Biochemical and biophysical research communications 2018 Sep 10;503(3):1968-1972
Biochemical and biophysical research communications 2018 Sep 10;503(3):1968-1972
Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline.
Bussian TJ, Aziz A, Meyer CF, Swenson BL, van Deursen JM, Baker DJ
Nature 2018 Oct;562(7728):578-582
Nature 2018 Oct;562(7728):578-582
L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease.
Polis B, Srikanth KD, Elliott E, Gil-Henn H, Samson AO
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2018 Oct;15(4):1036-1054
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2018 Oct;15(4):1036-1054
Phloroglucinol ameliorates cognitive impairments by reducing the amyloid β peptide burden and pro-inflammatory cytokines in the hippocampus of 5XFAD mice.
Yang EJ, Mahmood U, Kim H, Choi M, Choi Y, Lee JP, Cho JY, Hyun JW, Kim YS, Chang MJ, Kim HS
Free radical biology & medicine 2018 Oct;126:221-234
Free radical biology & medicine 2018 Oct;126:221-234
Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth.
Mao SPH, Park M, Cabrera RM, Christin JR, Karagiannis GS, Oktay MH, Zaiss DMW, Abrams SI, Guo W, Condeelis JS, Kenny PA, Segall JE
Breast cancer research : BCR 2018 Oct 26;20(1):131
Breast cancer research : BCR 2018 Oct 26;20(1):131
Endothelial Cell-Specific Inactivation of TSPAN12 (Tetraspanin 12) Reveals Pathological Consequences of Barrier Defects in an Otherwise Intact Vasculature.
Zhang C, Lai MB, Pedler MG, Johnson V, Adams RH, Petrash JM, Chen Z, Junge HJ
Arteriosclerosis, thrombosis, and vascular biology 2018 Nov;38(11):2691-2705
Arteriosclerosis, thrombosis, and vascular biology 2018 Nov;38(11):2691-2705
Lentivirus-mediated overexpression of OTULIN ameliorates microglia activation and neuroinflammation by depressing the activation of the NF-κB signaling pathway in cerebral ischemia/reperfusion rats.
Xu H, Qin W, Hu X, Mu S, Zhu J, Lu W, Luo Y
Journal of neuroinflammation 2018 Mar 15;15(1):83
Journal of neuroinflammation 2018 Mar 15;15(1):83
APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.
Lin YT, Seo J, Gao F, Feldman HM, Wen HL, Penney J, Cam HP, Gjoneska E, Raja WK, Cheng J, Rueda R, Kritskiy O, Abdurrob F, Peng Z, Milo B, Yu CJ, Elmsaouri S, Dey D, Ko T, Yankner BA, Tsai LH
Neuron 2018 Jun 27;98(6):1294
Neuron 2018 Jun 27;98(6):1294
Prostaglandin Signaling Governs Spike Timing-Dependent Plasticity at Sensory Synapses onto Mouse Spinal Projection Neurons.
Li J, Serafin E, Baccei ML
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Jul 25;38(30):6628-6639
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Jul 25;38(30):6628-6639
Blockade of soluble epoxide hydrolase attenuates post-ischemic neuronal hyperexcitation and confers resilience against stroke with TrkB activation.
Chang LH, Lin HC, Huang SS, Chen IC, Chu KW, Chih CL, Liang YW, Lee YC, Chen YY, Lee YH, Lee IH
Scientific reports 2018 Jan 8;8(1):118
Scientific reports 2018 Jan 8;8(1):118
Stress-Induced Neuronal Colony Stimulating Factor 1 Provokes Microglia-Mediated Neuronal Remodeling and Depressive-like Behavior.
Wohleb ES, Terwilliger R, Duman CH, Duman RS
Biological psychiatry 2018 Jan 1;83(1):38-49
Biological psychiatry 2018 Jan 1;83(1):38-49
Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture.
Marques-Torrejon MA, Gangoso E, Pollard SM
Disease models & mechanisms 2018 Feb 22;11(2)
Disease models & mechanisms 2018 Feb 22;11(2)
NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency.
Hou Y, Lautrup S, Cordonnier S, Wang Y, Croteau DL, Zavala E, Zhang Y, Moritoh K, O'Connell JF, Baptiste BA, Stevnsner TV, Mattson MP, Bohr VA
Proceedings of the National Academy of Sciences of the United States of America 2018 Feb 20;115(8):E1876-E1885
Proceedings of the National Academy of Sciences of the United States of America 2018 Feb 20;115(8):E1876-E1885
Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge.
Shemer A, Grozovski J, Tay TL, Tao J, Volaski A, Süß P, Ardura-Fabregat A, Gross-Vered M, Kim JS, David E, Chappell-Maor L, Thielecke L, Glass CK, Cornils K, Prinz M, Jung S
Nature communications 2018 Dec 6;9(1):5206
Nature communications 2018 Dec 6;9(1):5206
RGMa mediates reactive astrogliosis and glial scar formation through TGFβ1/Smad2/3 signaling after stroke.
Zhang R, Wu Y, Xie F, Zhong Y, Wang Y, Xu M, Feng J, Charish J, Monnier PP, Qin X
Cell death and differentiation 2018 Aug;25(8):1503-1516
Cell death and differentiation 2018 Aug;25(8):1503-1516
Localization of cannabinoid receptors CB1, CB2, GPR55, and PPARα in the canine gastrointestinal tract.
Galiazzo G, Giancola F, Stanzani A, Fracassi F, Bernardini C, Forni M, Pietra M, Chiocchetti R
Histochemistry and cell biology 2018 Aug;150(2):187-205
Histochemistry and cell biology 2018 Aug;150(2):187-205
Increased (pro)renin receptor expression in the subfornical organ of hypertensive humans.
Cooper SG, Trivedi DP, Yamamoto R, Worker CJ, Feng CY, Sorensen JT, Yang W, Xiong Z, Feng Y
American journal of physiology. Heart and circulatory physiology 2018 Apr 1;314(4):H796-H804
American journal of physiology. Heart and circulatory physiology 2018 Apr 1;314(4):H796-H804
Electroacupuncture Suppresses the NF-κB Signaling Pathway by Upregulating Cylindromatosis to Alleviate Inflammatory Injury in Cerebral Ischemia/Reperfusion Rats.
Jiang J, Luo Y, Qin W, Ma H, Li Q, Zhan J, Zhang Y
Frontiers in molecular neuroscience 2017;10:363
Frontiers in molecular neuroscience 2017;10:363
Dysfunction of Microglial STAT3 Alleviates Depressive Behavior via Neuron-Microglia Interactions.
Kwon SH, Han JK, Choi M, Kwon YJ, Kim SJ, Yi EH, Shin JC, Cho IH, Kim BH, Jeong Kim S, Ye SK
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2017 Sep;42(10):2072-2086
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2017 Sep;42(10):2072-2086
Injectable nanomedicine hydrogel for local chemotherapy of glioblastoma after surgical resection.
Bastiancich C, Bianco J, Vanvarenberg K, Ucakar B, Joudiou N, Gallez B, Bastiat G, Lagarce F, Préat V, Danhier F
Journal of controlled release : official journal of the Controlled Release Society 2017 Oct 28;264:45-54
Journal of controlled release : official journal of the Controlled Release Society 2017 Oct 28;264:45-54
Antarctic Krill Oil Diet Protects against Lipopolysaccharide-Induced Oxidative Stress, Neuroinflammation and Cognitive Impairment.
Choi JY, Jang JS, Son DJ, Im HS, Kim JY, Park JE, Choi WR, Han SB, Hong JT
International journal of molecular sciences 2017 Nov 28;18(12)
International journal of molecular sciences 2017 Nov 28;18(12)
Inhibitory effect of punicalagin on lipopolysaccharide-induced neuroinflammation, oxidative stress and memory impairment via inhibition of nuclear factor-kappaB.
Kim YE, Hwang CJ, Lee HP, Kim CS, Son DJ, Ham YW, Hellström M, Han SB, Kim HS, Park EK, Hong JT
Neuropharmacology 2017 May 1;117:21-32
Neuropharmacology 2017 May 1;117:21-32
Cell-type specific differences in promoter activity of the ALS-linked C9orf72 mouse ortholog.
Langseth AJ, Kim J, Ugolino JE, Shah Y, Hwang HY, Wang J, Bergles DE, Brown SP
Scientific reports 2017 Jul 18;7(1):5685
Scientific reports 2017 Jul 18;7(1):5685
Inhibitory effect of ethanol extract of Nannochloropsis oceanica on lipopolysaccharide-induced neuroinflammation, oxidative stress, amyloidogenesis and memory impairment.
Choi JY, Hwang CJ, Lee HP, Kim HS, Han SB, Hong JT
Oncotarget 2017 Jul 11;8(28):45517-45530
Oncotarget 2017 Jul 11;8(28):45517-45530
All- Trans-Retinoic Acid Augments the Histopathological Outcome of Neuroinflammation and Neurodegeneration in Lupus-Prone MRL/lpr Mice.
Theus MH, Sparks JB, Liao X, Ren J, Luo XM
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2017 Feb;65(2):69-81
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2017 Feb;65(2):69-81
Huperzine A alleviates neuroinflammation, oxidative stress and improves cognitive function after repetitive traumatic brain injury.
Mei Z, Zheng P, Tan X, Wang Y, Situ B
Metabolic brain disease 2017 Dec;32(6):1861-1869
Metabolic brain disease 2017 Dec;32(6):1861-1869
Electroacupuncture attenuates learning and memory impairment via activation of α7nAChR-mediated anti-inflammatory activity in focal cerebral ischemia/reperfusion injured rats.
Liu J, Li C, Peng H, Yu K, Tao J, Lin R, Chen L
Experimental and therapeutic medicine 2017 Aug;14(2):939-946
Experimental and therapeutic medicine 2017 Aug;14(2):939-946
HDAC3 inhibition ameliorates spinal cord injury by immunomodulation.
Kuboyama T, Wahane S, Huang Y, Zhou X, Wong JK, Koemeter-Cox A, Martini M, Friedel RH, Zou H
Scientific reports 2017 Aug 17;7(1):8641
Scientific reports 2017 Aug 17;7(1):8641
Progesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling.
Roche SL, Wyse-Jackson AC, Gómez-Vicente V, Lax P, Ruiz-Lopez AM, Byrne AM, Cuenca N, Cotter TG
PloS one 2016;11(11):e0165197
PloS one 2016;11(11):e0165197
Imbalances in Mobilization and Activation of Pro-Inflammatory and Vascular Reparative Bone Marrow-Derived Cells in Diabetic Retinopathy.
Chakravarthy H, Beli E, Navitskaya S, O'Reilly S, Wang Q, Kady N, Huang C, Grant MB, Busik JV
PloS one 2016;11(1):e0146829
PloS one 2016;11(1):e0146829
Upregulation of neuronal zinc finger protein A20 expression is required for electroacupuncture to attenuate the cerebral inflammatory injury mediated by the nuclear factor-kB signaling pathway in cerebral ischemia/reperfusion rats.
Zhan J, Qin W, Zhang Y, Jiang J, Ma H, Li Q, Luo Y
Journal of neuroinflammation 2016 Oct 3;13(1):258
Journal of neuroinflammation 2016 Oct 3;13(1):258
Xenin-induced feeding suppression is not mediated through the activation of central extracellular signal-regulated kinase signaling in mice.
Kim ER, Lew PS, Spirkina A, Mizuno TM
Behavioural brain research 2016 Oct 1;312:118-26
Behavioural brain research 2016 Oct 1;312:118-26
Acceleration of amyloidogenesis and memory impairment by estrogen deficiency through NF-κB dependent beta-secretase activation in presenilin 2 mutant mice.
Hwang CJ, Park MH, Choi MK, Choi JS, Oh KW, Hwang DY, Han SB, Hong JT
Brain, behavior, and immunity 2016 Mar;53:113-122
Brain, behavior, and immunity 2016 Mar;53:113-122
Reduction of cytosolic phospholipase A2α upregulation delays the onset of symptoms in SOD1G93A mouse model of amyotrophic lateral sclerosis.
Solomonov Y, Hadad N, Levy R
Journal of neuroinflammation 2016 Jun 1;13(1):134
Journal of neuroinflammation 2016 Jun 1;13(1):134
Hippocampus-based contextual memory alters the morphological characteristics of astrocytes in the dentate gyrus.
Choi M, Ahn S, Yang EJ, Kim H, Chong YH, Kim HS
Molecular brain 2016 Jul 26;9(1):72
Molecular brain 2016 Jul 26;9(1):72
Progesterone receptor signalling in retinal photoreceptor neuroprotection.
Jackson AC, Roche SL, Byrne AM, Ruiz-Lopez AM, Cotter TG
Journal of neurochemistry 2016 Jan;136(1):63-77
Journal of neurochemistry 2016 Jan;136(1):63-77
Seizure-Induced Sympathoexcitation Is Caused by Activation of Glutamatergic Receptors in RVLM That Also Causes Proarrhythmogenic Changes Mediated by PACAP and Microglia in Rats.
Bhandare AM, Kapoor K, Pilowsky PM, Farnham MM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Jan 13;36(2):506-17
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Jan 13;36(2):506-17
Dynamic changes in the relationship of microglia to cardiovascular neurons in response to increases and decreases in blood pressure.
Kapoor K, Bhandare AM, Nedoboy PE, Mohammed S, Farnham MM, Pilowsky PM
Neuroscience 2016 Aug 4;329:12-29
Neuroscience 2016 Aug 4;329:12-29
Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke.
Rodhe J, Burguillos MA, de Pablos RM, Kavanagh E, Persson A, Englund E, Deierborg T, Venero JL, Joseph B
Acta neuropathologica communications 2016 Aug 26;4(1):92
Acta neuropathologica communications 2016 Aug 26;4(1):92
Neuronal Injury, Gliosis, and Glial Proliferation in Two Models of Temporal Lobe Epilepsy.
Loewen JL, Barker-Haliski ML, Dahle EJ, White HS, Wilcox KS
Journal of neuropathology and experimental neurology 2016 Apr;75(4):366-78
Journal of neuropathology and experimental neurology 2016 Apr;75(4):366-78
Role of Acid Sphingomyelinase in Shifting the Balance Between Proinflammatory and Reparative Bone Marrow Cells in Diabetic Retinopathy.
Chakravarthy H, Navitskaya S, O'Reilly S, Gallimore J, Mize H, Beli E, Wang Q, Kady N, Huang C, Blanchard GJ, Grant MB, Busik JV
Stem cells (Dayton, Ohio) 2016 Apr;34(4):972-83
Stem cells (Dayton, Ohio) 2016 Apr;34(4):972-83
The PGRMC1 Protein Level Correlates with the Binding Activity of a Sigma-2 Fluorescent Probe (SW120) in Rat Brain Cells.
Zeng C, Garg N, Mach RH
Molecular imaging and biology 2016 Apr;18(2):172-9
Molecular imaging and biology 2016 Apr;18(2):172-9
Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium.
Yao J, Jia L, Khan N, Lin C, Mitter SK, Boulton ME, Dunaief JL, Klionsky DJ, Guan JL, Thompson DA, Zacks DN
Autophagy 2015;11(6):939-53
Autophagy 2015;11(6):939-53
Partial depletion of the proinflammatory monocyte population is neuroprotective in the myenteric plexus but not in the basal ganglia in a MPTP mouse model of Parkinson's disease.
Côté M, Poirier AA, Aubé B, Jobin C, Lacroix S, Soulet D
Brain, behavior, and immunity 2015 May;46:154-67
Brain, behavior, and immunity 2015 May;46:154-67
The role of cytosolic phospholipase A2 α in amyloid precursor protein induction by amyloid beta1-42 : implication for neurodegeneration.
Sagy-Bross C, Kasianov K, Solomonov Y, Braiman A, Friedman A, Hadad N, Levy R
Journal of neurochemistry 2015 Mar;132(5):559-71
Journal of neurochemistry 2015 Mar;132(5):559-71
Expression of Cytoplasmic Gelsolin in Rat Brain After Experimental Subarachnoid Hemorrhage.
Xie GB, Wang CX, Zhou CH, Li H, Zhang XS, Zhou XM, Zhang L, Hang CH, Zhou ML, Shi JX
Cellular and molecular neurobiology 2015 Jul;35(5):723-31
Cellular and molecular neurobiology 2015 Jul;35(5):723-31
The expression of interleukin-6 and its receptor in various brain regions and their roles in exploratory behavior and stress responses.
Aniszewska A, Chłodzińska N, Bartkowska K, Winnicka MM, Turlejski K, Djavadian RL
Journal of neuroimmunology 2015 Jul 15;284:1-9
Journal of neuroimmunology 2015 Jul 15;284:1-9
Vagus nerve stimulation attenuates cerebral ischemia and reperfusion injury via endogenous cholinergic pathway in rat.
Jiang Y, Li L, Liu B, Zhang Y, Chen Q, Li C
PloS one 2014;9(7):e102342
PloS one 2014;9(7):e102342
Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease.
Pisanu A, Lecca D, Mulas G, Wardas J, Simbula G, Spiga S, Carta AR
Neurobiology of disease 2014 Nov;71:280-91
Neurobiology of disease 2014 Nov;71:280-91
Domoic acid-induced seizures in California sea lions (Zalophus californianus) are associated with neuroinflammatory brain injury.
Kirkley KS, Madl JE, Duncan C, Gulland FM, Tjalkens RB
Aquatic toxicology (Amsterdam, Netherlands) 2014 Nov;156:259-68
Aquatic toxicology (Amsterdam, Netherlands) 2014 Nov;156:259-68
Regionally specific expression of high-voltage-activated calcium channels in thalamic nuclei of epileptic and non-epileptic rats.
Kanyshkova T, Ehling P, Cerina M, Meuth P, Zobeiri M, Meuth SG, Pape HC, Budde T
Molecular and cellular neurosciences 2014 Jul;61:110-22
Molecular and cellular neurosciences 2014 Jul;61:110-22
A small molecule binding HMGB1 and HMGB2 inhibits microglia-mediated neuroinflammation.
Lee S, Nam Y, Koo JY, Lim D, Park J, Ock J, Kim J, Suk K, Park SB
Nature chemical biology 2014 Dec;10(12):1055-60
Nature chemical biology 2014 Dec;10(12):1055-60
Aging-induced Nrf2-ARE pathway disruption in the subventricular zone drives neurogenic impairment in parkinsonian mice via PI3K-Wnt/β-catenin dysregulation.
L'Episcopo F, Tirolo C, Testa N, Caniglia S, Morale MC, Impagnatiello F, Pluchino S, Marchetti B
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jan 23;33(4):1462-85
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Jan 23;33(4):1462-85
Plasticity of subventricular zone neuroprogenitors in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease involves cross talk between inflammatory and Wnt/β-catenin signaling pathways: functional consequences for neuroprotection and repair.
L'Episcopo F, Tirolo C, Testa N, Caniglia S, Morale MC, Deleidi M, Serapide MF, Pluchino S, Marchetti B
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Feb 8;32(6):2062-85
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 Feb 8;32(6):2062-85
A-type K+ currents in intralaminar thalamocortical relay neurons.
Kanyshkova T, Broicher T, Meuth SG, Pape HC, Budde T
Pflugers Archiv : European journal of physiology 2011 May;461(5):545-56
Pflugers Archiv : European journal of physiology 2011 May;461(5):545-56
The performance of laminin-containing cryogel scaffolds in neural tissue regeneration.
Jurga M, Dainiak MB, Sarnowska A, Jablonska A, Tripathi A, Plieva FM, Savina IN, Strojek L, Jungvid H, Kumar A, Lukomska B, Domanska-Janik K, Forraz N, McGuckin CP
Biomaterials 2011 May;32(13):3423-34
Biomaterials 2011 May;32(13):3423-34
Regulation of toll-like receptor 1 and -2 in neonatal mice brains after hypoxia-ischemia.
Stridh L, Smith PL, Naylor AS, Wang X, Mallard C
Journal of neuroinflammation 2011 May 10;8:45
Journal of neuroinflammation 2011 May 10;8:45
Transmission and spreading of tauopathy in transgenic mouse brain.
Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, Fraser G, Stalder AK, Beibel M, Staufenbiel M, Jucker M, Goedert M, Tolnay M
Nature cell biology 2009 Jul;11(7):909-13
Nature cell biology 2009 Jul;11(7):909-13
Irradiation-induced loss of microglia in the young brain.
Kalm M, Lannering B, Björk-Eriksson T, Blomgren K
Journal of neuroimmunology 2009 Jan 3;206(1-2):70-5
Journal of neuroimmunology 2009 Jan 3;206(1-2):70-5
Intranigral lentiviral delivery of dominant-negative TNF attenuates neurodegeneration and behavioral deficits in hemiparkinsonian rats.
McCoy MK, Ruhn KA, Martinez TN, McAlpine FE, Blesch A, Tansey MG
Molecular therapy : the journal of the American Society of Gene Therapy 2008 Sep;16(9):1572-9
Molecular therapy : the journal of the American Society of Gene Therapy 2008 Sep;16(9):1572-9
Maternal hypothyroxinemia impairs spatial learning and synaptic nature and function in the offspring.
Opazo MC, Gianini A, Pancetti F, Azkcona G, Alarcón L, Lizana R, Noches V, Gonzalez PA, Marassi MP, Mora S, Rosenthal D, Eugenin E, Naranjo D, Bueno SM, Kalergis AM, Riedel CA
Endocrinology 2008 Oct;149(10):5097-106
Endocrinology 2008 Oct;149(10):5097-106
Glial reactions and degeneration of myelinated processes in spinal cord gray matter in chronic experimental autoimmune encephalomyelitis.
Wu J, Ohlsson M, Warner EA, Loo KK, Hoang TX, Voskuhl RR, Havton LA
Neuroscience 2008 Oct 15;156(3):586-96
Neuroscience 2008 Oct 15;156(3):586-96
Modulation of inflammatory responses after global ischemia by transplanted umbilical cord matrix stem cells.
Hirko AC, Dallasen R, Jomura S, Xu Y
Stem cells (Dayton, Ohio) 2008 Nov;26(11):2893-901
Stem cells (Dayton, Ohio) 2008 Nov;26(11):2893-901
P2Y12 receptor upregulation in activated microglia is a gateway of p38 signaling and neuropathic pain.
Kobayashi K, Yamanaka H, Fukuoka T, Dai Y, Obata K, Noguchi K
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Mar 12;28(11):2892-902
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Mar 12;28(11):2892-902
Contribution of TRPV1 to microglia-derived IL-6 and NFkappaB translocation with elevated hydrostatic pressure.
Sappington RM, Calkins DJ
Investigative ophthalmology & visual science 2008 Jul;49(7):3004-17
Investigative ophthalmology & visual science 2008 Jul;49(7):3004-17
Age-dependent accumulation of lipofuscin in perivascular and subretinal microglia in experimental mice.
Xu H, Chen M, Manivannan A, Lois N, Forrester JV
Aging cell 2008 Jan;7(1):58-68
Aging cell 2008 Jan;7(1):58-68
Intracarotid injection of fluorescence activated cell-sorted CD49d-positive neural stem cells improves targeted cell delivery and behavior after stroke in a mouse stroke model.
Guzman R, De Los Angeles A, Cheshier S, Choi R, Hoang S, Liauw J, Schaar B, Steinberg G
Stroke 2008 Apr;39(4):1300-6
Stroke 2008 Apr;39(4):1300-6
The synthetic peroxisome proliferator-activated receptor-gamma agonist ciglitazone attenuates neuroinflammation and accelerates encapsulation in bacterial brain abscesses.
Kielian T, Syed MM, Liu S, Phulwani NK, Phillips N, Wagoner G, Drew PD, Esen N
Journal of immunology (Baltimore, Md. : 1950) 2008 Apr 1;180(7):5004-16
Journal of immunology (Baltimore, Md. : 1950) 2008 Apr 1;180(7):5004-16
The synthetic peroxisome proliferator-activated receptor-gamma agonist ciglitazone attenuates neuroinflammation and accelerates encapsulation in bacterial brain abscesses.
Kielian T, Syed MM, Liu S, Phulwani NK, Phillips N, Wagoner G, Drew PD, Esen N
Journal of immunology (Baltimore, Md. : 1950) 2008 Apr 1;180(7):5004-16
Journal of immunology (Baltimore, Md. : 1950) 2008 Apr 1;180(7):5004-16
Glial activation links early-life seizures and long-term neurologic dysfunction: evidence using a small molecule inhibitor of proinflammatory cytokine upregulation.
Somera-Molina KC, Robin B, Somera CA, Anderson C, Stine C, Koh S, Behanna HA, Van Eldik LJ, Watterson DM, Wainwright MS
Epilepsia 2007 Sep;48(9):1785-1800
Epilepsia 2007 Sep;48(9):1785-1800
C3d binding to the myelin oligodendrocyte glycoprotein results in an exacerbated experimental autoimmune encephalomyelitis.
Jégou JF, Chan P, Schouft MT, Griffiths MR, Neal JW, Gasque P, Vaudry H, Fontaine M
Journal of immunology (Baltimore, Md. : 1950) 2007 Mar 1;178(5):3323-31
Journal of immunology (Baltimore, Md. : 1950) 2007 Mar 1;178(5):3323-31
C3d binding to the myelin oligodendrocyte glycoprotein results in an exacerbated experimental autoimmune encephalomyelitis.
Jégou JF, Chan P, Schouft MT, Griffiths MR, Neal JW, Gasque P, Vaudry H, Fontaine M
Journal of immunology (Baltimore, Md. : 1950) 2007 Mar 1;178(5):3323-31
Journal of immunology (Baltimore, Md. : 1950) 2007 Mar 1;178(5):3323-31
Expression of allograft inflammatory factor 1 in tissues from patients with systemic sclerosis and in vitro differential expression of its isoforms in response to transforming growth factor beta.
Del Galdo F, Maul GG, Jiménez SA, Artlett CM
Arthritis and rheumatism 2006 Aug;54(8):2616-25
Arthritis and rheumatism 2006 Aug;54(8):2616-25
IRT-1, a novel interferon-gamma-responsive transcript encoding a growth-suppressing basic leucine zipper protein.
Autieri MV, Agrawal N
The Journal of biological chemistry 1998 Jun 12;273(24):14731-7
The Journal of biological chemistry 1998 Jun 12;273(24):14731-7
IRT-1, a novel interferon-gamma-responsive transcript encoding a growth-suppressing basic leucine zipper protein.
Autieri MV, Agrawal N
The Journal of biological chemistry 1998 Jun 12;273(24):14731-7
The Journal of biological chemistry 1998 Jun 12;273(24):14731-7
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Supportive validation
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- Western Blot: AIF-1/Iba1 Antibody [NB100-1028] - Staining of human frontal cortex (A), Rat Brain (B), Mouse Brain (C), and Pig Brain (D) lysates (35 ug protein in RIPA buffer). Antibody at 1 ug/mL. Detected by chemiluminescence.
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- Western Blot: AIF-1/Iba1 Antibody [NB100-1028] - Staining of Human (A) with antibody at 1 ug/mL and of Mouse (B) and Rat (C) with antibody at 0.5 ug/mL. Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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- Western Blot: AIF-1/Iba1 Antibody [NB100-1028] - Staining of Human Lymph node (Molecular weight: 16.7 KDa) (A), Mouse Brain (B) and Rat Brain (C) lysate with AIF-1/Iba1 Antibody at 1 ug/mL (35 ug protein in RIPA buffer). Detected by chemiluminescence.
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- Immunohistochemistry-Frozen: AIF-1/Iba1 Antibody [NB100-1028] - Staining in rat hippocampus at 40x. Image from a verified customer review.
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- Immunohistochemistry: AIF-1/Iba1 Antibody [NB100-1028] - Staining in canine optic nerve. Image from a verified customer review.
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- Immunohistochemistry: AIF-1/Iba1 Antibody [NB100-1028] - Staining in Mouse brain. Image from a verified customer review.
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- Immunohistochemistry-Frozen: AIF-1/Iba1 Antibody [NB100-1028] - Immunoreacitiy in a mouse spinal cord after focal injection of lysolecitithin into the ventral column white matter. Image from a verified customer review.
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- Immunohistochemistry-Frozen: AIF-1/Iba1 Antibody [NB100-1028] - Mouse spinal cord microglia staining in frozen sections. Image from a verified customer review.
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- Immunohistochemistry Whole-Mount: AIF-1/Iba1 Antibody [NB100-1028] - Mouse dorsal root ganglia. AIF-1/Iba1 expression in reactive macrophages. Maximum intensity z-projection from 3D images. IHC image submitted by a verified customer review.
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- Immunohistochemistry-Frozen: AIF-1/Iba1 Antibody [NB100-1028] - Feline optic nerve microglia were immunolabeled with AIF-1/Iba1 Antibody (green), DAPI (blue). Imaging was performed using an epifluorescence microscope. IHC-Fr image submitted by a verified customer review.
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- Immunohistochemistry-Paraffin: AIF-1/Iba1 Antibody [NB100-1028] - Staining in mouse brain using AIF-1/Iba1 Antibody. IHC-P image submitted by a verified customer review.
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- Immunohistochemistry-Paraffin: AIF-1/Iba1 Antibody [NB100-1028] - Brown arrow= AIF-1/Iba1 positive cells, Green arrow= mTOR positive cells, Black arrow= mTOR and AIF-1/Iba1 positive cells. IHC-P image submitted by a verified customer review.
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- Immunohistochemistry-Paraffin: AIF-1/Iba1 Antibody [NB100-1028] - Staining of paraffin embedded Mouse Lung using AIF-1/Iba1 Antibody. Heat induced antigen retrieval with Tris-EDTA pH 9, HRP-Staining (1:500).
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- Immunohistochemistry Free-Floating: AIF-1/Iba1 Antibody [NB100-1028] - Reactive microglia (green) in peritumoral area of IC injected human glioblastoma cells in mouse brain. NeuN (red), DAPI (blue). at 1:250. IHC image submitted by a verified customer review.
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- Immunohistochemistry Free-Floating: AIF-1/Iba1 Antibody [NB100-1028] - Staining in mouse brain using . IHC image submitted by a verified customer review.
