Tissue expression
Cell line expression
Protein structure
GDF7
Growth differentiation factor 7BMP12
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016]
Top validated antibodies |
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LSBio | LS-C413385 | Polyclonal |
WB
IHC |
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Biorbyt | orb157097 | Polyclonal |
WB
EL
ICC
IHC |
||
antibodies-online | ABIN393235 | 5 references | Monoclonal |
EL
|
|
St John's Laboratory | STJ97349 | Polyclonal |
WB
EL
ICC
IHC |
||
Cusabio Biotech Co., Ltd | CSB-PA768769LA01HU | Polyclonal |
WB
EL
IHC
|
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider