CCT6B

This gene encodes a molecular chaperone that is a member of the chaperonin-containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

Description

Chaperonin containing TCP1 subunit 6B

Tissue specificity

Tissue enriched (testis)

Subcell location

Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

17 (34927859 - 34981078)

Ensembl ID

ENSG00000132141  (ver. 103.38)

Orthologs

Mouse Cct6b: ENSMUSG00000020698

UniProt

Q92526

neXtProt

NX_Q92526

Human splice variants
Mouse splice variants

Protein structure