BS7850

antibody from Bioworld Technology, Inc
Targeting: CDKAL1 FLJ20342
Provider product page for BS7850
Western blot
Immunohistochemistry

Antibody data

Product number
BS7850 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CDKAL1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CDKAL1.
Description
Cell cycle progression is controlled, in part, by a family of cyclin dependent kinases (Cdks) that work to phosphorylate key substrates involved in each phase of cell cycle progression. Cdks are the catalytic subunits of serine/threonine protein kinases, a large family of proteins that act as regulators of the eukaryotic cell cycle. CDKAL1 (Cdk5 regulatory subunit associated protein 1-like 1) is a 579 amino acid single-pass membrane protein that contains one TRAM domain and is similar to Cdk5 regulatory subunit associated proteins (CDK5RAPs). Expressed in pancreas, brain and skeletal muscle, CDKAL1 uses iron as a cofactor and is involved in glucose-stimulated insulin secretion. Defects in the gene encoding CDKAL1 impair insulin secretion and are associated with the development of type 2 diabetes. Multiple isoforms of CDKAL1 exist due to alternative splicing events.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CDKAL1 protein structure - BS7850 shown in red.