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Protein structure
ARHGAP26
Rho GTPase activating protein 26GRAF, KIAA0621, OPHN1L, OPHN1L1
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
Top validated antibodies |
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| Proteintech Group |  17747-1-AP |
1 references | Polyclonal |
WB
EL
IP
IHC
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| Atlas Antibodies | HPA035107 |
1 references | Polyclonal |
WB
IHC
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| Novus Biologicals | NBP1-89732 |
2 references | Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | 17747-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| Abnova Corporation | PAB3298 |
3 references | Polyclonal |
WB
IHC
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