BS7839

antibody from Bioworld Technology, Inc
Targeting: WARS1 IFI53, IFP53, WARS
Provider product page for BS7839
Western blot
Immunohistochemistry

Antibody data

Product number
BS7839 - Provider product page
Provider
Bioworld Technology, Inc
Product name
WARS polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human WARS.
Description
Tryptophanyl-tRNA synthetases are essential enzymes that catalyze the aminoacylation of tRNA(trp) with tryptophan, an essential function of the protein synthesis machinery of the cell. Two forms of tryptophanyl-tRNA synthetase exist: a cytoplasmic form, named TrpRS (also known as WARS), and a mitochondrial form, named WARS2. In normal cells, human TrpRS exists as a full length form and as a truncated form designated mini TrpRS, which is produced by alternative splicing. Expression of mini TrpRs is highly stimulated in human cells by the addition of IFN-gamma. Although both human full-length TrpRS and mini TrpRS are enzymatically active in aminoacylation, they differ in angiostatic activity. The gene encoding human TrpRS maps to chromosome 14q32.31 and the gene encoding human WARS2 maps to chromosome 1p13.3-p13.1. The first 18 amino acids of WARS2 constitute the mitochondrial localization signal sequence.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
WARS1 protein structure - BS7839 shown in red.