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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [1]
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- Product number
- PAB2593 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2593, RRID:AB_1578286
- Product name
- OPRS1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of OPRS1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references An unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for butyrophenones.
Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells.
Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: biochemical and physiological evidences, consequences in neuroprotection.
Lee IT, Chen S, Schetz JA
European journal of pharmacology 2008 Jan 14;578(2-3):123-36
European journal of pharmacology 2008 Jan 14;578(2-3):123-36
Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells.
Cobos EJ, del Pozo E, Baeyens JM
Journal of neurochemistry 2007 Aug;102(3):812-25
Journal of neurochemistry 2007 Aug;102(3):812-25
Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: biochemical and physiological evidences, consequences in neuroprotection.
Maurice T, Grégoire C, Espallergues J
Pharmacology, biochemistry, and behavior 2006 Aug;84(4):581-97
Pharmacology, biochemistry, and behavior 2006 Aug;84(4):581-97
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of OPRS1 (arrow) using rabbit OPRS1 polyclonal antibody (Cat # PAB2593). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OPRS1 gene (Lane 2) (Origene Technologies).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Flow cytometric analysis of NCI-H292 cells using OPRS1 polyclonal antibody (Cat # PAB2593)(bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
- Validation comment
- Flow Cytometry
