BS8362

antibody from Bioworld Technology, Inc
Targeting: PNPLA3 adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon
Provider product page for BS8362
Western blot
Immunohistochemistry

Antibody data

Product number
BS8362 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PNPLA3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PNPLA3.
Description
ADPN, a member of the Adiponutrin family, displays lipase activity that is dependent upon the presence of an activated serine residue. D-glucose elicits a 7-fold increase in ADPN mRNA levels, and insulin has a slight effect on ADPN expression in the presence or absence of glucose. The glucose-induced increase in ADPN expression can be reversed by factors known to raise intracellular cAMP. mRNA ADPN levels are negatively correlated with fasting glucose levels and subjects with high ADPN mRNA levels have increased insulin sensitivity, implicating ADPN in obesity and diabetes. ADPN gene expression in humans is highly regulated by changes in energy balance. In mice adipocytes, ADPN parallels the expression of fatty acid synthase (FAS) and Srebp1c, a variant of Srebp1.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PNPLA3 protein structure - BS8362 shown in red.