BS8172

antibody from Bioworld Technology, Inc
Targeting: IREB2 IRP2
Provider product page for BS8172
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8172 - Provider product page
Provider
Bioworld Technology, Inc
Product name
IREB2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human IREB2.
Description
?Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins: IRP-1 and -2 (iron regulatory protein-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IRE-BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.
Reactivity
Human, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
IREB2 protein structure - BS8172 shown in red.