FNab00558

antibody from FineTest Biotech

Targeting: ARHGEF1 LBCL2, P115-RHOGEF, SUB1.5

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

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Validation data

Product number: FNab00558 - Provider product page
Provider: FineTest Biotech
Product name: ARHGEF1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: Rho guanine nucleotide exchange fac tor(GEF) 1
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ARHGEF1 protein structure - FNab00558 shown in red.