Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- AF1958 - Provider product page
- Provider
- R&D Systems
- Product name
- Human/Mouse GDF-11/BMP-11 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human and mouse GDF-11/BMP-11 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human/mouse/rat GDF-8/Myostatin and less than 1% cross-reactivity with recombinant human BMP-6 is observed.
- Reactivity
- Human, Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
O95390
- Isotype
- IgG
- Vial size
- 100 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure.
Zhang XJ, Tan H, Shi ZF, Li N, Jia Y, Hao Z
Molecular medicine reports 2019 May;19(5):4109-4118
Molecular medicine reports 2019 May;19(5):4109-4118
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- GDF-11/BMP-11 in Mouse Embryo. GDF-11/BMP-11 was detected in immersion fixed frozen sections of mouse embryo (11 d.p.c.) using Goat Anti-Human/Mouse GDF-11/BMP-11 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1958) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to dorsal root ganglia. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.