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- Antibody Data
- Antigen structure
- References [18]
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- Product number
- MA5-14040 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-Moesin Monoclonal Antibody (38/87), Biotin
- Antibody type
- Monoclonal
- Antigen
- Purifed from natural sources
- Description
- MA5-14043 targets Moesin in IF, IHC (P), IP, and WB applications and shows reactivity with Bovine, Human, and Rat samples. The MA5-14043 immunogen is moesin purified from cow uterus.
- Reactivity
- Human, Rat, Bovine
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Antibody clone number
- 38/87
- Vial size
- 500 µL
- Concentration
- 0.2 mg/ml
- Storage
- 4° C
Submitted references Signal-dependent slow leukocyte rolling does not require cytoskeletal anchorage of P-selectin glycoprotein ligand-1 (PSGL-1) or integrin αLβ2.
Differential expression of moesin in breast cancers and its implication in epithelial-mesenchymal transition.
Distinct cellular and therapeutic effects of obatoclax in rituximab-sensitive and -resistant lymphomas.
The effect of sphingomyelin synthase 2 (SMS2) deficiency on the expression of drug transporters in mouse brain.
Distinct molecular mechanisms responsible for bortezomib-induced death of therapy-resistant versus -sensitive B-NHL cells.
TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans.
Anti-moesin antibodies in the serum of patients with aplastic anemia stimulate peripheral blood mononuclear cells to secrete TNF-alpha and IFN-gamma.
Acquired resistance to rituximab is associated with chemotherapy resistance resulting from decreased Bax and Bak expression.
Adhesion molecules as prognostic markers in pancreatic adenocarcinoma.
Age-related defects in moesin/ezrin cytoskeletal signals in mouse CD4 T cells.
Specific antibodies to moesin, a membrane-cytoskeleton linker protein, are frequently detected in patients with acquired aplastic anemia.
Differential tissue and subcellular expressionof ERM proteins in normal and malignant tissues: cytoplasmic ezrin expression has prognostic signficance for head and neck squamous cell carcinoma.
Ezrin promotes ovarian carcinoma cell invasion and its retained expression predicts poor prognosis in ovarian carcinoma.
Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine.
Chemokine stimulation of human peripheral blood T lymphocytes induces rapid dephosphorylation of ERM proteins, which facilitates loss of microvilli and polarization.
Molecular profiling of bladder cancer using cDNA microarrays: defining histogenesis and biological phenotypes.
Ezrin and moesin expression within the developing human cerebrum and tuberous sclerosis-associated cortical tubers.
ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse.
Shao B, Yago T, Coghill PA, Klopocki AG, Mehta-D'souza P, Schmidtke DW, Rodgers W, McEver RP
The Journal of biological chemistry 2012 Jun 1;287(23):19585-98
The Journal of biological chemistry 2012 Jun 1;287(23):19585-98
Differential expression of moesin in breast cancers and its implication in epithelial-mesenchymal transition.
Wang CC, Liau JY, Lu YS, Chen JW, Yao YT, Lien HC
Histopathology 2012 Jul;61(1):78-87
Histopathology 2012 Jul;61(1):78-87
Distinct cellular and therapeutic effects of obatoclax in rituximab-sensitive and -resistant lymphomas.
Brem EA, Thudium K, Khubchandani S, Tsai PC, Olejniczak SH, Bhat S, Riaz W, Gu J, Iqbal A, Campagna R, Knight J, Mavis C, Hoskin P, Deeb G, Gibbs JF, Fetterly G, Czuczman MS, Hernandez-Ilizaliturri FJ
British journal of haematology 2011 Jun;153(5):599-611
British journal of haematology 2011 Jun;153(5):599-611
The effect of sphingomyelin synthase 2 (SMS2) deficiency on the expression of drug transporters in mouse brain.
Zhang Y, Dong J, Zhu X, Wang W, Yang Q
Biochemical pharmacology 2011 Aug 1;82(3):287-94
Biochemical pharmacology 2011 Aug 1;82(3):287-94
Distinct molecular mechanisms responsible for bortezomib-induced death of therapy-resistant versus -sensitive B-NHL cells.
Olejniczak SH, Blickwedehl J, Belicha-Villanueva A, Bangia N, Riaz W, Mavis C, Clements JL, Gibbs J, Hernandez-Ilizaliturri FJ, Czuczman MS
Blood 2010 Dec 16;116(25):5605-14
Blood 2010 Dec 16;116(25):5605-14
TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans.
Washington AV, Gibot S, Acevedo I, Gattis J, Quigley L, Feltz R, De La Mota A, Schubert RL, Gomez-Rodriguez J, Cheng J, Dutra A, Pak E, Chertov O, Rivera L, Morales J, Lubkowski J, Hunter R, Schwartzberg PL, McVicar DW
The Journal of clinical investigation 2009 Jun;119(6):1489-501
The Journal of clinical investigation 2009 Jun;119(6):1489-501
Anti-moesin antibodies in the serum of patients with aplastic anemia stimulate peripheral blood mononuclear cells to secrete TNF-alpha and IFN-gamma.
Takamatsu H, Espinoza JL, Lu X, Qi Z, Okawa K, Nakao S
Journal of immunology (Baltimore, Md. : 1950) 2009 Jan 1;182(1):703-10
Journal of immunology (Baltimore, Md. : 1950) 2009 Jan 1;182(1):703-10
Acquired resistance to rituximab is associated with chemotherapy resistance resulting from decreased Bax and Bak expression.
Olejniczak SH, Hernandez-Ilizaliturri FJ, Clements JL, Czuczman MS
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Mar 1;14(5):1550-60
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Mar 1;14(5):1550-60
Adhesion molecules as prognostic markers in pancreatic adenocarcinoma.
Torer N, Kayaselcuk F, Nursal TZ, Yildirim S, Tarim A, Nòyan T, Karakayali H
Journal of surgical oncology 2007 Oct 1;96(5):419-23
Journal of surgical oncology 2007 Oct 1;96(5):419-23
Age-related defects in moesin/ezrin cytoskeletal signals in mouse CD4 T cells.
Garcia GG, Sadighi Akha AA, Miller RA
Journal of immunology (Baltimore, Md. : 1950) 2007 Nov 15;179(10):6403-9
Journal of immunology (Baltimore, Md. : 1950) 2007 Nov 15;179(10):6403-9
Specific antibodies to moesin, a membrane-cytoskeleton linker protein, are frequently detected in patients with acquired aplastic anemia.
Takamatsu H, Feng X, Chuhjo T, Lu X, Sugimori C, Okawa K, Yamamoto M, Iseki S, Nakao S
Blood 2007 Mar 15;109(6):2514-20
Blood 2007 Mar 15;109(6):2514-20
Differential tissue and subcellular expressionof ERM proteins in normal and malignant tissues: cytoplasmic ezrin expression has prognostic signficance for head and neck squamous cell carcinoma.
Madan R, Brandwein-Gensler M, Schlecht NF, Elias K, Gorbovitsky E, Belbin TJ, Mahmood R, Breining D, Qian H, Childs G, Locker J, Smith R, Haigentz M Jr, Gunn-Moore F, Prystowsky MB
Head & neck 2006 Nov;28(11):1018-27
Head & neck 2006 Nov;28(11):1018-27
Ezrin promotes ovarian carcinoma cell invasion and its retained expression predicts poor prognosis in ovarian carcinoma.
Köbel M, Gradhand E, Zeng K, Schmitt WD, Kriese K, Lantzsch T, Wolters M, Dittmer J, Strauss HG, Thomssen C, Hauptmann S
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2006 Apr;25(2):121-30
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2006 Apr;25(2):121-30
Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine.
Saotome I, Curto M, McClatchey AI
Developmental cell 2004 Jun;6(6):855-64
Developmental cell 2004 Jun;6(6):855-64
Chemokine stimulation of human peripheral blood T lymphocytes induces rapid dephosphorylation of ERM proteins, which facilitates loss of microvilli and polarization.
Brown MJ, Nijhara R, Hallam JA, Gignac M, Yamada KM, Erlandsen SL, Delon J, Kruhlak M, Shaw S
Blood 2003 Dec 1;102(12):3890-9
Blood 2003 Dec 1;102(12):3890-9
Molecular profiling of bladder cancer using cDNA microarrays: defining histogenesis and biological phenotypes.
Sanchez-Carbayo M, Socci ND, Charytonowicz E, Lu M, Prystowsky M, Childs G, Cordon-Cardo C
Cancer research 2002 Dec 1;62(23):6973-80
Cancer research 2002 Dec 1;62(23):6973-80
Ezrin and moesin expression within the developing human cerebrum and tuberous sclerosis-associated cortical tubers.
Johnson MW, Miyata H, Vinters HV
Acta neuropathologica 2002 Aug;104(2):188-96
Acta neuropathologica 2002 Aug;104(2):188-96
ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse.
Allenspach EJ, Cullinan P, Tong J, Tang Q, Tesciuba AG, Cannon JL, Takahashi SM, Morgan R, Burkhardt JK, Sperling AI
Immunity 2001 Nov;15(5):739-50
Immunity 2001 Nov;15(5):739-50
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Supportive validation
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- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded human placenta stained with Moesin antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of endothelial cells.
- Conjugate
- Biotin
