orb131883

antibody from Biorbyt

Targeting: FBXW7 AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10

Western blot (Data presented on provider website)

Antibody Data

Product number

orb131883

Provider

Biorbyt

Product name

FBXW7 antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal to FBXW7. F-box/WD repeat-containing protein 7 (FBXW7) is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXW7 probably recognizes and binds to phosphorylated target proteins. Furthermore, FBXW7 is involved in the degradation of cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Vial size

100 ul

Concentration

100 μg/ml BSA

Storage

-20°C