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antibody from antibodies-online
Targeting: HSPA1A
HSP70-1, HSPA1
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Immunocytochemistry Immunoprecipitation Immunohistochemistry
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- Antibody Data
- Antigen structure
- References [12]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [3]
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- Product number
- ABIN266936 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Heat Shock Protein Cognate 4 (HSC70-4) antibody
- Antibody type
- Monoclonal
- Description
- Unpurified
- Reactivity
- Human, Mouse, Rat, Bovine, Feline, Hamster, Simian
- Host
- Mouse
- Isotype
- IgM
- Antibody clone number
- 13D3
- Vial size
- 0.05 mL
- Storage
- Store at -20°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Early involvement of lysosome dysfunction in the degeneration of cerebral cortical neurons caused by the lipid peroxidation product 4-hydroxynonenal.
Twelve hours of heat stress induces inflammatory signaling in porcine skeletal muscle.
α-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2.
Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage.
STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy.
Interplay of LRRK2 with chaperone-mediated autophagy.
Chaperone-mediated autophagy targets hypoxia-inducible factor-1α (HIF-1α) for lysosomal degradation.
Altered lipid content inhibits autophagic vesicular fusion.
Heat shock cognate protein 70 is involved in rotavirus cell entry.
Platelet adhesion to collagen under flow causes dissociation of a phosphoprotein complex of heat-shock proteins and protein phosphatase 1.
Protein and peptide binding and stimulation of in vitro lysosomal proteolysis by the 73-kDa heat shock cognate protein.
Heat-shock cognate protein (hsc71) and related proteins in mouse spermatogenic cells.
Zhang S, Eitan E, Mattson MP
Journal of neurochemistry 2017 Mar;140(6):941-954
Journal of neurochemistry 2017 Mar;140(6):941-954
Twelve hours of heat stress induces inflammatory signaling in porcine skeletal muscle.
Ganesan S, Reynolds C, Hollinger K, Pearce SC, Gabler NK, Baumgard LH, Rhoads RP, Selsby JT
American journal of physiology. Regulatory, integrative and comparative physiology 2016 Jun 1;310(11):R1288-96
American journal of physiology. Regulatory, integrative and comparative physiology 2016 Jun 1;310(11):R1288-96
α-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2.
Kett LR, Stiller B, Bernath MM, Tasset I, Blesa J, Jackson-Lewis V, Chan RB, Zhou B, Di Paolo G, Przedborski S, Cuervo AM, Dauer WT
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Apr 8;35(14):5724-42
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Apr 8;35(14):5724-42
Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage.
Park C, Suh Y, Cuervo AM
Nature communications 2015 Apr 16;6:6823
Nature communications 2015 Apr 16;6:6823
STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy.
Ferreira JV, Fôfo H, Bejarano E, Bento CF, Ramalho JS, Girão H, Pereira P
Autophagy 2013 Sep;9(9):1349-66
Autophagy 2013 Sep;9(9):1349-66
Interplay of LRRK2 with chaperone-mediated autophagy.
Orenstein SJ, Kuo SH, Tasset I, Arias E, Koga H, Fernandez-Carasa I, Cortes E, Honig LS, Dauer W, Consiglio A, Raya A, Sulzer D, Cuervo AM
Nature neuroscience 2013 Apr;16(4):394-406
Nature neuroscience 2013 Apr;16(4):394-406
Chaperone-mediated autophagy targets hypoxia-inducible factor-1α (HIF-1α) for lysosomal degradation.
Hubbi ME, Hu H, Kshitiz, Ahmed I, Levchenko A, Semenza GL
The Journal of biological chemistry 2013 Apr 12;288(15):10703-14
The Journal of biological chemistry 2013 Apr 12;288(15):10703-14
Altered lipid content inhibits autophagic vesicular fusion.
Koga H, Kaushik S, Cuervo AM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Aug;24(8):3052-65
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Aug;24(8):3052-65
Heat shock cognate protein 70 is involved in rotavirus cell entry.
Guerrero CA, Bouyssounade D, Zárate S, Isa P, López T, Espinosa R, Romero P, Méndez E, López S, Arias CF
Journal of virology 2002 Apr;76(8):4096-102
Journal of virology 2002 Apr;76(8):4096-102
Platelet adhesion to collagen under flow causes dissociation of a phosphoprotein complex of heat-shock proteins and protein phosphatase 1.
Polanowska-Grabowska R, Simon CG Jr, Falchetto R, Shabanowitz J, Hunt DF, Gear AR
Blood 1997 Aug 15;90(4):1516-26
Blood 1997 Aug 15;90(4):1516-26
Protein and peptide binding and stimulation of in vitro lysosomal proteolysis by the 73-kDa heat shock cognate protein.
Terlecky SR, Chiang HL, Olson TS, Dice JF
The Journal of biological chemistry 1992 May 5;267(13):9202-9
The Journal of biological chemistry 1992 May 5;267(13):9202-9
Heat-shock cognate protein (hsc71) and related proteins in mouse spermatogenic cells.
Maekawa M, O'Brien DA, Allen RL, Eddy EM
Biology of reproduction 1989 Apr;40(4):843-52
Biology of reproduction 1989 Apr;40(4):843-52
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