CINP

The protein encoded by this gene is reported to be a component of the DNA replication complex as well as a genome-maintenance protein. It may interact with proteins important for replication initiation and has been shown to bind chromatin at the G1 phase of the cell cycle and dissociate from chromatin with replication initiation. It may also serve to regulate checkpoint signaling as part of the DNA damage response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Description

Cyclin dependent kinase 2 interacting protein

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

14 (102341102 - 102362916)

Ensembl ID

ENSG00000100865  (ver. 103.38)

Orthologs

Mouse Cinp: ENSMUSG00000021276

UniProt

Q9BW66

neXtProt

NX_Q9BW66

Human splice variants
Mouse splice variants

Protein structure