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Protein structure
TRIM2
Tripartite motif containing 2CMT2R, KIAA0517, RNF86
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Top validated antibodies |
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| Novus Biologicals |  NB100-1218 |
2 references | Polyclonal |
WB
EL
IP
IHC
FC
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| Proteintech Group | 20356-1-AP |
1 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | 20356-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| antibodies-online | ABIN249847 |
2 references | Polyclonal |
WB
EL
IP
IHC
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| Everest Biotech | EB05914 |
Polyclonal |
WB
EL
IHC
FC
|
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