AMM03815G

antibody from Leading Biology

Targeting: MS4A2 APY, FCER1B, IGER, MS4A1

Western blot (Recommended by provider)

Antibody Data

Product number

AMM03815G

Provider

Leading Biology

Product name

MS4A2 Antibody (monoclonal) (M02)

Antibody type

Monoclonal

Description

The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of family members.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

3B1

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.