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- Validations
- Western blot [1]
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- Immunohistochemistry [1]
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- Product number
- ABIN953390 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mesoderm Development Candidate 2 (MESDC2) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 0.1 mg
Submitted references A cell-based Dkk1 binding assay reveals roles for extracellular domains of LRP5 in Dkk1 interaction and highlights differences between wild-type and the high bone mass mutant LRP5(G171V).
Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd.
Fusion of the SUMO/Sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25).
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Murrills RJ, Matteo JJ, Bhat BM, Coleburn VE, Allen KM, Chen W, Damagnez V, Bhat RA, Bex FJ, Bodine PV
Journal of cellular biochemistry 2009 Dec 1;108(5):1066-75
Journal of cellular biochemistry 2009 Dec 1;108(5):1066-75
Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd.
Li Y, Lu W, He X, Bu G
FEBS letters 2006 Oct 2;580(22):5423-8
FEBS letters 2006 Oct 2;580(22):5423-8
Fusion of the SUMO/Sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25).
Veltman IM, Vreede LA, Cheng J, Looijenga LH, Janssen B, Schoenmakers EF, Yeh ET, van Kessel AG
Human molecular genetics 2005 Jul 15;14(14):1955-63
Human molecular genetics 2005 Jul 15;14(14):1955-63
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A
Genome research 2003 Oct;13(10):2265-70
Genome research 2003 Oct;13(10):2265-70
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- MESDC2 Antibody (C-term) (Cat. #AP52669PU-N) western blot analysis in Hela,293,HepG2 cell line lysates (35μg/lane).This demonstrates the MESDC2 antibody detected the MESDC2 protein (arrow).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Confocal immunofluorescent analysis of MESDC2 Antibody (C-term)(Cat#AP52669PU-N) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- MESDC2 Antibody (C-term)(Cat. #AP52669PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MESDC2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
