BS5594

antibody from Bioworld Technology, Inc
Targeting: ABCB7 ABC7, ASAT, Atm1p, EST140535
Provider product page for BS5594
Western blot
Immunohistochemistry

Antibody data

Product number
BS5594 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ABCB7 polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 707-752 of Human ABCB7.
Description
The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1ÿ4 that are known to be present in the human peroxisome membrane. All four proteins are ABC half-transporters, which dimerize to form an active transporter. A mutation in the ABCD1 causes X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage. ABCD2 in mouse, is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD. The peroxisomal membrane comprises 2 quantitatively major proteins, PMP22 and ABCD3. ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors. ABCD4 localizes to peroxisomes. ABCB7 is a half-transporter involved in the transport of heme from the mitochondria to the cytosol and maps to human chromosome Xq13.1-q13.3.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ABCB7 protein structure - BS5594 shown in red.