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Protein structure
GPT2
Glutamic--pyruvic transaminase 2ALT2
This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Top validated antibodies |
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| Proteintech Group |  16757-1-AP |
30 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | 16757-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| NovoPro Bioscience Inc. | 111147 |
Polyclonal |
WB
EL
ICC
IP
IHC
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| FineTest Biotech | FNab03620 |
Polyclonal |
WB
EL
IP
IHC
|
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| Novus Biologicals | H00084706-M04 |
Monoclonal |
WB
EL
ICC
|
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