DNAJA2

The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro. [provided by RefSeq, Jul 2008]

Description

DnaJ heat shock protein family (Hsp40) member A2

Tissue specificity

Low tissue specificity

Subcell location

Nucleoli, Intermediate filaments, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

16 (46955362 - 46973674)

Ensembl ID

ENSG00000069345  (ver. 103.38)

Orthologs

Mouse Dnaja2: ENSMUSG00000031701

UniProt

O60884

neXtProt

NX_O60884

Human splice variants
Mouse splice variants

Protein structure