Tissue expressionAmygdalaBasal gangliaCerebellumCerebral cortexChoroid plexusHippocampal formationHypothalamusMedulla oblongataMidbrainOlfactory bulbPonsSpinal cordThalamusWhite matterRetinaAdrenal glandParathyroid glandPituitary glandThyroid glandLungEsophagusSalivary glandTongueColonDuodenumRectumSmall intestineStomachGallbladderLiverPancreasKidneyUrinary bladderEpididymisProstateSeminal vesicleTestisBreastCervixEndometriumFallopian tubeOvaryPlacentaVaginaHeart muscleSkeletal muscleSmooth muscleAdipose tissueSkinAppendixBone marrowLymph nodeSpleenThymusTonsil02004006008001,000
Cell line expressionAF22GAMGSH-SY5YU-138 MGU-251 MGU-87 MGHTCEpiHTERT-RPE1OE19CACO-2Hep G2CAPAN-2HEK 293NTERA-2RPTEC TERT1RT4PC-3SuSaA-431HaCaTSK-MEL-30WM-115A549HBEC3-KTSCLC-21HAN3-CABEWOEFO-21HeLaHTERT-HME1MCF7SiHaSK-BR-3T-47dHUVEC TERT2TIMEHSkMCASC diffASC TERT1BJBJ hTERT+BJ hTERT+ SV40 Large T+BJ hTERT+ SV40 Large T+ RasG12VFHDF/TERT166HBF TERT88HHSteCLHCN-M2RH-30U-2 OSU-2197DaudiHDLM-2HTEC/SVTERT24-BJURKATKarpas-707MOLT-4REHRPMI-8226U-266/70U-266/84U-698HAP1HELHL-60HMC-1K-562NB-4THP-1U-9370510152025
Protein structure

TDO2

Tryptophan 2,3-dioxygenase
TDO, TPH2 
This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]
More gene data

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                        347 antibodies from 26 providers.

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                        Proteintech Group
                        1 antibody
                        Novus Biologicals
                        55 antibodies
                        Invitrogen Antibodies
                        26 antibodies
                        OriGene
                        49 antibodies
                        antibodies-online
                        76 antibodies
                        Abnova Corporation
                        5 antibodies
                        Aviva Systems Biology
                        4 antibodies
                        R&D Systems
                        8 antibodies
                        GeneTex
                        2 antibodies
                        Bioworld Technology, Inc
                        1 antibody
                        Biorbyt
                        18 antibodies
                        Antibodies.com
                        7 antibodies
                        NovoPro Bioscience Inc.
                        4 antibodies
                        FineTest Biotech
                        1 antibody
                        St John's Laboratory
                        2 antibodies
                        ProSci
                        2 antibodies
                        Abbexa
                        2 antibodies
                        Abcepta
                        1 antibody
                        United States Biological
                        26 antibodies
                        Creative Biolabs
                        7 antibodies
                        Leading Biology
                        3 antibodies
                        MyBioSource
                        2 antibodies
                        Creative Diagnostics
                        6 antibodies
                        MilliporeSigma / Merck KGaA
                        2 antibodies
                        Acris Antibodies GmbH
                        2 antibodies