CABT-B10005

antibody from Creative Diagnostics

Targeting: COL18A1 KNO, KNO1, KS

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-B10005

Provider

Creative Diagnostics

Product name

Mouse anti-Human COL18A1 monoclonal antibody, clone LU69

Antibody type

Monoclonal

Description

This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Mouse monoclonal antibody raised against recombinant COL18A1.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

LU69

Vial size

100 _l

Storage

4°C short term only, for routine storage, aliquot and freeze at -20°C