Tissue expression
Cell line expression
Protein structure
GDF1
Growth differentiation factor 1This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. The encoded protein is translated from a bicistronic mRNA that also encodes ceramide synthase 1. Mutations in this gene are associated with several congenital cardiovascular malformations. [provided by RefSeq, Jul 2016]
Top validated antibodies |
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LSBio | LS-B8884 | Polyclonal |
WB
EL
ICC
IHC |
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Boster Biological Technology | A07609-1 | Polyclonal |
WB
EL
ICC
|
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OriGene | AP11940PU-N | Polyclonal |
WB
IHC |
||
Acris Antibodies GmbH | AP11940PU-N | Polyclonal |
WB
IHC |
||
Abgent | AP2063a | Polyclonal |
WB
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
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Recommended by provider