Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- ABIN1450104 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Reactivity
- Human, Mouse
- Host
- Chicken/Avian
- Vial size
- 0.1 mg
Submitted references Siva1 is a XIAP-interacting protein that balances NFkappaB and JNK signalling to promote apoptosis.
Siva is an apoptosis-selective p53 target gene important for neuronal cell death.
Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway.
CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein.
Resch U, Schichl YM, Winsauer G, Gudi R, Prasad K, de Martin R
Journal of cell science 2009 Aug 1;122(Pt 15):2651-61
Journal of cell science 2009 Aug 1;122(Pt 15):2651-61
Siva is an apoptosis-selective p53 target gene important for neuronal cell death.
Jacobs SB, Basak S, Murray JI, Pathak N, Attardi LD
Cell death and differentiation 2007 Jul;14(7):1374-85
Cell death and differentiation 2007 Jul;14(7):1374-85
Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway.
Py B, Slomianny C, Auberger P, Petit PX, Benichou S
Journal of immunology (Baltimore, Md. : 1950) 2004 Apr 1;172(7):4008-17
Journal of immunology (Baltimore, Md. : 1950) 2004 Apr 1;172(7):4008-17
CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein.
Prasad KV, Ao Z, Yoon Y, Wu MX, Rizk M, Jacquot S, Schlossman SF
Proceedings of the National Academy of Sciences of the United States of America 1997 Jun 10;94(12):6346-51
Proceedings of the National Academy of Sciences of the United States of America 1997 Jun 10;94(12):6346-51
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of SIVA in mouse liver tissue lysate with SIVA antibody at 1 ug/mL.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunofluorescence of SIVA in mouse liver cells with SIVA antibody at 20 ug/mL.