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- Antigen structure
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- Flow cytometry [1]
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- Product number
- ABIN953279 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-MAF1 Homolog (S. Cerevisiae) (MAF1) (AA 97-125), (Middle Region) antibody
- Antibody type
- Polyclonal
- Description
- Protein A column, followed by peptide affinity purification
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 97-125, Middle Region
- Vial size
- 0.4 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Requirement of the mTOR kinase for the regulation of Maf1 phosphorylation and control of RNA polymerase III-dependent transcription in cancer cells.
mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1.
Mammalian Maf1 is a negative regulator of transcription by all three nuclear RNA polymerases.
Human Maf1 negatively regulates RNA polymerase III transcription via the TFIIB family members Brf1 and Brf2.
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
Shor B, Wu J, Shakey Q, Toral-Barza L, Shi C, Follettie M, Yu K
The Journal of biological chemistry 2010 May 14;285(20):15380-92
The Journal of biological chemistry 2010 May 14;285(20):15380-92
mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1.
Kantidakis T, Ramsbottom BA, Birch JL, Dowding SN, White RJ
Proceedings of the National Academy of Sciences of the United States of America 2010 Jun 29;107(26):11823-8
Proceedings of the National Academy of Sciences of the United States of America 2010 Jun 29;107(26):11823-8
Mammalian Maf1 is a negative regulator of transcription by all three nuclear RNA polymerases.
Johnson SS, Zhang C, Fromm J, Willis IM, Johnson DL
Molecular cell 2007 May 11;26(3):367-79
Molecular cell 2007 May 11;26(3):367-79
Human Maf1 negatively regulates RNA polymerase III transcription via the TFIIB family members Brf1 and Brf2.
Rollins J, Veras I, Cabarcas S, Willis I, Schramm L
International journal of biological sciences 2007 May 1;3(5):292-302
International journal of biological sciences 2007 May 1;3(5):292-302
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
Lamesch P, Li N, Milstein S, Fan C, Hao T, Szabo G, Hu Z, Venkatesan K, Bethel G, Martin P, Rogers J, Lawlor S, McLaren S, Dricot A, Borick H, Cusick ME, Vandenhaute J, Dunham I, Hill DE, Vidal M
Genomics 2007 Mar;89(3):307-15
Genomics 2007 Mar;89(3):307-15
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Supportive validation
- Submitted by
- antibodies-online (provider)
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- IHC
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
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