MSMO1

Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

Methylsterol monooxygenase 1

Tissue specificity

Tissue enhanced (liver)

Subcell location

Endoplasmic reticulum

Predicted location

Membrane

Protein family

Disease related genes
Enzymes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Potential drug targets
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

4 (165327667 - 165343164)

Ensembl ID

ENSG00000052802  (ver. 103.38)

Orthologs

Mouse Msmo1: ENSMUSG00000031604

UniProt

Q15800

neXtProt

NX_Q15800

Human splice variants
Mouse splice variants

Protein structure