Tissue expression
Cell line expression
Protein structure
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1LH1, LLH, PLOD
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Top validated antibodies |
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antibodies-online | ABIN2845847 | 1 references | Polyclonal |
WB
IHC
FC
|
|
Proteintech Group | 12475-1-AP | 2 references | Polyclonal |
WB
EL
IHC
|
|
Novus Biologicals | NBP2-38770 | 2 references | Polyclonal |
WB
IHC |
|
NovoPro Bioscience Inc. | 123554 | Polyclonal |
WB
EL
IHC
FC |
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Invitrogen Antibodies | 29480-1-AP150UL | Polyclonal |
WB
ICC
IHC
|
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