AKTIP

gene product
FLJ13258, FTS
The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
63 antibodies from 13 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Atlas Antibodies
2 antibodies
Novus Biologicals
9 antibodies
antibodies-online
15 antibodies
Abnova Corporation
6 antibodies
Proteintech Group
1 antibody
Aviva Systems Biology
2 antibodies
Acris Antibodies GmbH
1 antibody
LifeSpan BioSciences, Inc.
8 antibodies
Creative Biomart
6 antibodies
United States Biological
9 antibodies
GeneTex
2 antibodies
Abgent
1 antibody
Sigma-Aldrich
1 antibody