BS60777

antibody from Bioworld Technology, Inc
Targeting: PALLD CGI-151, KIAA0992, SIH002
Provider product page for BS60777

Antibody data

Product number
BS60777 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PALLD polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human PALLD
Description
Palladin, also known as PALLD, PNCA1 or SIH002, is a 1,383 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains five immunoglobulin (Ig)-like domains. Expressed as several alternatively spliced isoforms that are found in kidney, prostate, ovary and colon, palladin functions as a cytoskeletal protein that is required both for the organization of the Actin cytoskeleton, as well as for the establishment of proper cell motility, cell adhesion and cell-matrix interactions. Palladin interacts with Eps8, LASP-1 and VASP and may also play a role in cytoskeletal scaffolding and Actin remodeling. In response to DNA damage, palladin is subject to phosphorylation on select serine residues. Defects in the gene encoding palladin may increase genetic susceptibility to pancreatic cancer, strongly suggesting a role for palladin in tumorigenesis.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PALLD protein structure - BS60777 shown in red.