KLHL4

This gene encodes a member of the kelch family of proteins, which are characterized by kelch repeat motifs and a POZ/BTB protein-binding domain. It is thought that kelch repeats are actin binding domains. However, the specific function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Description

Kelch like family member 4

Tissue specificity

Tissue enhanced (adrenal gland, brain)

Subcell location

Microtubules, Centriolar satellite

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

X (87517409 - 87670050)

Ensembl ID

ENSG00000102271  (ver. 103.38)

Orthologs

Mouse Klhl4: ENSMUSG00000025597

UniProt

Q9C0H6

neXtProt

NX_Q9C0H6

Human splice variants
Mouse splice variants

Protein structure