MYO1A

This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin-1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with autosomal dominant deafness. Alternatively spliced variants have been found for this gene. [provided by RefSeq, Dec 2011]

Description

Myosin IA

Tissue specificity

Tissue enriched (intestine)

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

12 (57028517 - 57051198)

Ensembl ID

ENSG00000166866  (ver. 103.38)

Orthologs

Mouse Myo1a: ENSMUSG00000025401

UniProt

Q9UBC5

neXtProt

NX_Q9UBC5

Human splice variants
Mouse splice variants

Protein structure