Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PAB16736 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB16736, RRID:AB_10677830
- Product name
- FTO polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of FTO.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain.
Regulation of Fto/Ftm gene expression in mice and humans.
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.
Fredriksson R, Hägglund M, Olszewski PK, Stephansson O, Jacobsson JA, Olszewska AM, Levine AS, Lindblom J, Schiöth HB
Endocrinology 2008 May;149(5):2062-71
Endocrinology 2008 May;149(5):2062-71
Regulation of Fto/Ftm gene expression in mice and humans.
Stratigopoulos G, Padilla SL, LeDuc CA, Watson E, Hattersley AT, McCarthy MI, Zeltser LM, Chung WK, Leibel RL
American journal of physiology. Regulatory, integrative and comparative physiology 2008 Apr;294(4):R1185-96
American journal of physiology. Regulatory, integrative and comparative physiology 2008 Apr;294(4):R1185-96
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.
Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, Najjar S, Nagaraja R, Orrú M, Usala G, Dei M, Lai S, Maschio A, Busonero F, Mulas A, Ehret GB, Fink AA, Weder AB, Cooper RS, Galan P, Chakravarti A, Schlessinger D, Cao A, Lakatta E, Abecasis GR
PLoS genetics 2007 Jul;3(7):e115
PLoS genetics 2007 Jul;3(7):e115
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of FTO in human uterus tissue lysate with FTO polyclonal antibody (Cat # PAB16736) at (A) 1 and (B) 2 ug/mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemistry of FTO in mouse brain tissue with FTO polyclonal antibody (Cat # PAB16736) at 2.5 ug/mL .
- Validation comment
- Immunohistochemistry