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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
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- Product number
- H00026229-B01P - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00026229-B01P, RRID:AB_1236696
- Product name
- Mouse Polyclonal beta-1,3-Glucuronyltransferase 3/B3GAT3 Antibody
- Antibody type
- Polyclonal
- Description
- Protein A purified. B3GAT3 - beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I),
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Functional validation of novel compound heterozygous variants in B3GAT3 resulting in severe osteopenia and fractures: expanding the disease phenotype.
Skeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia is caused by a novel mutation in B3GAT3.
Faulty initiation of proteoglycan synthesis causes cardiac and joint defects.
Activation of TonEBP by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc.
Job F, Mizumoto S, Smith L, Couser N, Brazil A, Saal H, Patterson M, Gibson MI, Soden S, Miller N, Thiffault I, Saunders C, Yamada S, Hoffmann K, Sugahara K, Farrow E
BMC medical genetics 2016 Nov 21;17(1):86
BMC medical genetics 2016 Nov 21;17(1):86
Skeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia is caused by a novel mutation in B3GAT3.
Budde BS, Mizumoto S, Kogawa R, Becker C, Altmüller J, Thiele H, Rüschendorf F, Toliat MR, Kaleschke G, Hämmerle JM, Höhne W, Sugahara K, Nürnberg P, Kennerknecht I
Human genetics 2015 Jul;134(7):691-704
Human genetics 2015 Jul;134(7):691-704
Faulty initiation of proteoglycan synthesis causes cardiac and joint defects.
Baasanjav S, Al-Gazali L, Hashiguchi T, Mizumoto S, Fischer B, Horn D, Seelow D, Ali BR, Aziz SA, Langer R, Saleh AA, Becker C, Nürnberg G, Cantagrel V, Gleeson JG, Gomez D, Michel JB, Stricker S, Lindner TH, Nürnberg P, Sugahara K, Mundlos S, Hoffmann K
American journal of human genetics 2011 Jul 15;89(1):15-27
American journal of human genetics 2011 Jul 15;89(1):15-27
Activation of TonEBP by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc.
Hiyama A, Gajghate S, Sakai D, Mochida J, Shapiro IM, Risbud MV
The Journal of biological chemistry 2009 Apr 10;284(15):9824-34
The Journal of biological chemistry 2009 Apr 10;284(15):9824-34
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: beta-1,3-Glucuronyltransferase 3/B3GAT3 Antibody [H00026229-B01P] - Analysis of B3GAT3 expression in transfected 293T cell line by B3GAT3 polyclonal antibody. Lane 1: B3GAT3 transfected lysate(36.85 KDa). Lane 2: Non-transfected lysate.
