CTSV

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011]

Description

Cathepsin V

Tissue specificity

Tissue enriched (lymphoid tissue)

Subcell location

Nucleoplasm, Nucleoli fibrillar center, Plasma membrane, Cytosol

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

9 (97029677 - 97156556)

Ensembl ID

ENSG00000136943  (ver. 103.38)

Orthologs

-

UniProt

O60911

neXtProt

NX_O60911

Human splice variants

Protein structure