BCAS1

This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Apr 2016]

Description

Brain enriched myelin associated protein 1

Tissue specificity

Tissue enhanced (brain, choroid plexus)

Subcell location

Vesicles

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

20 (53936777 - 54070594)

Ensembl ID

ENSG00000064787  (ver. 103.38)

Orthologs

Mouse Bcas1: ENSMUSG00000013523

UniProt

O75363

neXtProt

NX_O75363

Human splice variants
Mouse splice variants

Protein structure