ABIN401255

antibody from antibodies-online

Targeting: USP7 HAUSP

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN401255

Provider

antibodies-online

Product name

anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide corresponding to amino acids near the amino terminus of Human HAUSPprotein

Reactivity

Human, Mouse, Rat, Bovine, Canine

Host

Rabbit

Isotype

IgG

Vial size

0.1 mg

Concentration

0.98 mg/ml (by UV absorbance at 280 nm)

Storage

Store the antibody undiluted at 2-8°C for one month or for longer (in aliquots) at -20°C orbelow. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf life: one year from despatch.

References

Submitted references

Molecular recognition of p53 and MDM2 by USP7/HAUSP.

Sheng Y, Saridakis V, Sarkari F, Duan S, Wu T, Arrowsmith CH, Frappier L
Nature structural & molecular biology 2006 Mar;13(3):285-91

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Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7.

Boutell C, Canning M, Orr A, Everett RD
Journal of virology 2005 Oct;79(19):12342-54

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Expression and functional analyses of mHAUSP regulating apoptosis of cervical adenocarcinoma cells.

Yoo KJ, Lee HJ, Lee H, Lee KY, Lee SH, Chung HM, Baek KH
International journal of oncology 2005 Jul;27(1):97-104

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A dynamic role of HAUSP in the p53-Mdm2 pathway.

Li M, Brooks CL, Kon N, Gu W
Molecular cell 2004 Mar 26;13(6):879-86

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Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization.

Li M, Chen D, Shiloh A, Luo J, Nikolaev AY, Qin J, Gu W
Nature 2002 Apr 11;416(6881):648-53